Results 101 to 110 of about 1,172,309 (299)

Control Of Nonlinear Distributed Parameter Systems [PDF]

open access: yes, 2001
Shape sensitivity analysis in hyperbolic problems with non-smooth domains unbounded growth of total variations of snapshots of the 1D linear wave equation due to the chaotic behaviour of iterates of composite nonlinear boundary reflection relations velocity method and courant metric topologies in shape analysis of partial differential equations ...
openaire   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Approximate controllability of distributed systems by distributed controllers

open access: yesElectronic Journal of Differential Equations, 2005
Approximate controllability problem for a linear distributed control system with possibly unbounded input operator, connected in a series to another distributed system without control is investigated.
Benzion Shklyar, Vladimir Marchenko
doaj  

$H_\infty$ Piecewise Control for Linear Parabolic Distributed Parameter Systems With Piecewise Observation in Space

open access: yesIEEE Access, 2019
In this paper, the H∞ piecewise control problem is discussed for linear parabolic distributed parameter systems (DPSs) with piecewise observation in space. An H∞ performance constraint is provided in this paper to solve the effect caused by
Yaqiang Liu, Changyin Sun
doaj   +1 more source

System identification for modeling for control of flexible structures [PDF]

open access: yes
The major components of a design and operational flight strategy for flexible structure control systems are presented. In this strategy an initial distributed parameter control design is developed and implemented from available ground test data and on ...
Mettler, Edward, Milman, Mark
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Factorization and reduction methods for optimal control of distributed parameter systems [PDF]

open access: yes
A Chandrasekhar-type factorization method is applied to the linear-quadratic optimal control problem for distributed parameter systems. An aeroelastic control problem is used as a model example to demonstrate that if computationally efficient algorithms,
Burns, J. A., Powers, R. K.
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Application of optical distributed sensing and computation to control of large space structures [PDF]

open access: yes
A real time holographic sensing technique is introduced and its advantages are investigated from the filtering and control point of view. A feature of holographic sensing is its capability to make distributed measurements of the position and velocity of ...
Balakrishnan, A. V.
core   +1 more source

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