Results 121 to 130 of about 19,448,095 (300)
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Distributed Adaptive Control for Uncertain Networks
Control of network systems with uncertain local dynamics has remained an open problem for a long time. In this paper, a distributed minimax adaptive control algorithm is proposed for such networks whose local dynamics has an uncertain parameter possibly ...
Rantzer, Anders, +3 more
core +1 more source
Mitigating the Effects of Sensor and Actuator Attacks in Uncertain Networked Multiagent Systems
AerospaceThis paper presents a novel distributed robust adaptive control architecture for leader–follower networked multiagent systems with static undirected communication graph topologies to mitigate the effects of time-varying sensor and actuator attacks, and ...
Dhruva Venkat +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
On the Modelling of Distributed Real-time Control Applications
, 1995 The Controller Area Network (CAN) constitutes a good low level base for distributed real–time control systems. The priority mechanism allows for tailoring by choice of scheduling policy.
Martin Törngren, Törngren, Martin,
core +1 more source
Control-Oriented Modeling of Distributed Parameter Systems [PDF]
, 2020 In this paper the use of linear, time-invariant, distributed parameter systems {LTI-DPS) as models of physical processes is considered from a control viewpoint.
Associate Professor and Director, C N Nett +2 more
core
IEEE AccessDeep learning has emerged as a cornerstone technology across various domains, from image classification to natural language processing. However, the computational and data demands of training large-scale neural networks pose significant challenges ...
Nikodimos Provatas +2 more
doaj +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source