Results 81 to 90 of about 184,554 (316)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
IET Control Theory & Applications, 2021 In this paper, a control scheme based on state prediction is proposed for a class of nonlinear systems subject to input delay and external disturbance. Firstly, as for constant input delay, an improved control scheme that combining state prediction with ...
Bing Zhu, Mou Chen, Tao Li
doaj +1 more source
Control-Oriented Modeling of Distributed Parameter Systems [PDF]
, 2020 In this paper the use of linear, time-invariant, distributed parameter systems {LTI-DPS) as models of physical processes is considered from a control viewpoint.
Associate Professor and Director, C N Nett +2 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Robust reference tracking control design for nonlinear distributed parameter systems: fuzzy approach
, 2012 [[abstract]]This paper addresses a robust reference tracking control problem for nonlinear distributed parameter systems with external disturbances and measurement noises.
Y. T. Chang;B. S. Chen
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Linear Model Predictive Control for a Coupled CSTR and Axial Dispersion Tubular Reactor with Recycle
Mathematics, 2020 This manuscript addresses a novel output model predictive controller design for a representative model of continuous stirred-tank reactor (CSTR) and axial dispersion reactor with recycle. The underlying model takes the form of ODE-PDE in series and it is
Seyedhamidreza Khatibi +2 more
doaj +1 more source
On the Control of Distributed Parameter Systems using a Multidimensional Systems Setting
, 2008 The unique characteristic of a repetitive process is a series of sweeps, termed passes, through a set of dynamics defined over a finite duration with resetting before the start of the each new one.
Rogers, E +4 more
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