Results 151 to 160 of about 20,378,439 (303)

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Distributed Event-Triggered Adaptive Control for Consensus of Actuator Fault Multiagent Systems With Parameter Uncertainty and External Disturbances

Discrete Dynamics in Nature and Society
The leader–follower consensus problem in the presence of parameter uncertainty and external disturbances is investigated for multiagent systems (MASs) with actuator faults, which are based on event-triggered control.
Xiaofeng Cheng, Xisheng Zhan, Na Zhao, Jie Wu   +3 more
doaj   +1 more source

Computational Aspect of Distributed Parameter Control Systems [PDF]

application/pdfRecently, a great deal of research work of distributed parameter control systems has been carried out by scientists and engineers. By combining the finite element method with dynamic linear programming, the finite element and dynamic ...
フタガミ, タネヒロ, 二神, 種弘, 尾形, 裕之, Ogata, Hiroyuki, オガタ, ヒロユキ, Futagami, Tanehiro   +5 more
core  

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Predictive Control for a Class of Distributed Parameter Systems

, 2007
Focus the extension of the predictive control theory to a class of distributed parameter systems. Predictive control is one of the control strategies, which optimize control action within some horizon, in order to make the predicted processus behavior as
Wertz, Vincent, Abouzaid, Bouchra, Achhab, M.E.   +2 more
core  

On the control problem of the vibrating systems with distributed parameters

, 2004
Bu makalede, bir boyutlu zamandan bağımsız homojen olmayan dağılmış parametreli titreşim sistemleri için verilen başlangıç halinde denge durumunda olmayan fakat sonradan sonlu zaman aralığında denge durumuna getirilen kontrol problemi ele alındı. Bu kontrol problemi L2[0,T) Hilbert uzayındaki kontrol problemine denk olduğu gösterilmiştir. Sonuç olarak,
Ekinci, Hülya Yıldırım, Mustafayev, Mammad İ.   +1 more
openaire   +3 more sources