Results 81 to 90 of about 1,562,117 (345)
Optimum Design in Distributed Parameter Systems
Abstract A new numerical method for the computation of sensitivity of design performance functional with respect to boundary variations is used to study the optimum design problems in general distributed parameter systems. The method is based on a modification of schemes in functional derivative sensitivity analysis and includes a specialization of ...
openaire +1 more source
On the problem of modeling for parameter identification in distributed structures [PDF]
Structures are often characterized by parameters, such as mass and stiffness, that are spatially distributed. Parameter identification of distributed structures is subject to many of the difficulties involved in the modeling problem, and the choice of ...
Meirovitch, Leonard, Norris, Mark A.
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
We show that the nearest-neighbor spacing distribution for a model that consists of random points uniformly distributed on a self-similar fractal is the Brody distribution of random matrix theory.
B. B. Mandelbrot +10 more
core +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
An approximation theory for the identification of nonlinear distributed parameter systems [PDF]
An abstract approximation framework for the identification of nonlinear distributed parameter systems is developed. Inverse problems for nonlinear systems governed by strongly maximal monotone operators (satisfying a mild continuous dependence condition ...
Banks, H. T. +2 more
core +1 more source
An Observation Theory for Distributed-Parameter Systems [PDF]
This paper introduces a series of problems on state estimation for parabolic systems on the basis of measurements generated by sensors in the presence of unknown but bounded disturbances. Observability issues, guaranteed filtering schemes for distributed
Khapalov, A.Y., Kurzhanski, A.B.
core
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
This paper presents an optimal fault-tolerant control (FTC) method for dynamic systems with distributed fault parameter uncertainty. According to the distributed characteristic of the fault parameter uncertainty domain and insufficient fault information,
Dan Du, Zetao Li
doaj +1 more source

