Results 91 to 100 of about 256,344 (266)

Calculation of a Hydrodynamic Component of Behaviour of Heat-Transfer Agent in the Main Pipelines

open access: yesМеханика машин, механизмов и материалов, 2008
The design procedure of installation is developed for an estimation of behaviour of heat-transfer agent in the main pipelines, as distributed parameter systems.
N.A. Avtushenko, G.S. Lenevsky
doaj  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Optimal Fault-Tolerant Control for Dynamic Systems with Distributed Fault Parameter Uncertainty Domains

open access: yesAin Shams Engineering Journal
This paper presents an optimal fault-tolerant control (FTC) method for dynamic systems with distributed fault parameter uncertainty. According to the distributed characteristic of the fault parameter uncertainty domain and insufficient fault information,
Dan Du, Zetao Li
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Ant System Initial Parameters Distribution

open access: yesElektronika ir Elektrotechnika, 2011
The paper presents some preliminary results on distributing initial parameter values among ants in Ant System. Two cases are studied, one with uniform distribution of heuristic information sensitivity values among ants and other with Gaussian distribution.
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Mathematical Modelling of Transient Processes in a Section of an Electricity Network with Varying Configurations of its Components

open access: yesElektronika ir Elektrotechnika
This article presents mathematical models of power grid segments. Three load configurations representing real power systems were analysed. The mathematical models were developed using a field-circuit approach.
Andriy Chaban   +4 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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