Results 81 to 90 of about 256,344 (266)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

A New Type of Distributed Parameter Control Systems: Two-Point Boundary Value Problems for Infinite-Dimensional Dynamical Systems

Journal of Applied Mathematics, 2013
This survey note describes a new type of distributed parameter control systems—the two-point boundary value problems for infinite-dimensional dynamical systems, particularly, for hyperbolic systems of partial differential equations of second order, some ...
De-Xing Kong, Fa Wu
doaj   +1 more source

Optimum Design in Distributed Parameter Systems

IFAC Proceedings Volumes, 1983
Abstract A new numerical method for the computation of sensitivity of design performance functional with respect to boundary variations is used to study the optimum design problems in general distributed parameter systems. The method is based on a modification of schemes in functional derivative sensitivity analysis and includes a specialization of ...
openaire   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Adaptive control strategies for a class of nonlinear propagation bioprocesses [PDF]

Acta Montanistica Slovaca, 2008
This paper presents the control problem of a class of propagation bioprocesses that are carried out in fixed bed reactors. Since the dynamics of these processes are described by partial differential equations, in order to obtain useful models for control
Dan Popescu, Dan Selisteanu, Emil Petre
doaj  

Obtaining Mode Shapes through the Karhunen-Loève Expansion for Distributed-Parameter Linear Systems

Shock and Vibration, 2002
The Karhunen-Loève expansion is a powerful spectral technique for the analysis and synthesis of dynamical systems. It consists in decomposing a spatial correlation matrix, which can be obtained through numerical or physical experiments. The decomposition
Claudio Wolter, Marcelo A. Trindade, Rubens Sampaio   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Identification for distributed parameter systems [PDF]

This thesis considers the parameter identification problem for systems governed by partial differential equations. The various identification methods sire grouped into three disjoint classes namely: "Direct Methods", "Reduction to a Lumped Parameter System", and "Reduction to an Algebraic Equation".\ud The major subject investigated here is concerned ...
openaire   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source