Results 31 to 40 of about 1,794,273 (287)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

A Novel Robust Hybrid Control Strategy for a Quadrotor Trajectory Tracking Aided with Bioinspired Neural Dynamics

Applied Sciences
This paper introduces a novel hybrid control strategy for quadrotor UAVs inspired by neural dynamics. Our approach effectively addresses two common issues: the velocity jump problem in traditional backstepping control and the control signal chattering in
Jianqi Li, Xin Li, Jianquan Lu, Binfang Cao, Jian Sun   +4 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A rapid evaluation method for propulsion and aerodynamic characteristics and stall characteristics of distributed electric propulsion UAV

Xibei Gongye Daxue Xuebao
A distributed electric propulsion (DEP) aircraft can achieve its ultra-short takeoff and landing distance by utilizing the coupling effect of distributed propellers and wing surface to increase lift.
ZONG Jia, ZHOU Zhou, SHAO Zhuang, LI Minghao, ZHU Jinhong   +4 more
doaj   +1 more source

Drag Reduction by Wingtip-Mounted Propellers in Distributed Propulsion Configurations

Fluids, 2022
Tip-mounted propellers can increase wing aerodynamic efficiency, and the concept is gaining appeal in the context of hybrid electrical propulsion for greener aviation, as smaller and lighter electrical motors can help with mitigating structural drawbacks
Mauro Minervino, Giovanni Andreutti, Lorenzo Russo, Renato Tognaccini   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Hydrodynamic Assessment of Distributed Propulsion Systems for Shallow-Draft Inland Vessels

Polish Maritime Research
This study investigates the hydrodynamic performance of three distributed propulsion configurations with distinct hull shapes. The influence of duct design and hull geometry on thrust, absorbed power, and the resulting thrust-to-power ratio is explored ...
Jurkovic Martin, Illes Ladislav, Sosedová Jarmila, Prabowo Aditya Rio, Melnyk Oleksiy, Stopka Ondrej   +5 more
doaj   +1 more source

Lift enhancement characteristics of distributed propulsion wing with propulsion-aerodynamic coupling

Kongqi donglixue xuebao
To reconcile the high-lift demands of short takeoff and landing (STOL) with the requirement for efficient cruise in unmanned aerial vehicles (UAVs), this paper presents a novel distributed propulsion wing lift enhancement configuration (DPWLEC) that ...
Jingting YANG, Kelei WANG, Zhou ZHOU, Jia ZENG   +3 more
doaj   +1 more source

Changes in propulsion technique and shoulder complex loading following low-intensity wheelchair practice in novices. [PDF]

PLoS ONE, 2018
BACKGROUND:Up to 80% of wheelchair users are affected by shoulder pain. The Clinical Practice Guidelines for preservation of upper limb function following spinal cord injury suggest that using a proper wheelchair propulsion technique could minimize the ...
Marika T Leving, Riemer J K Vegter, Wiebe H K de Vries, Sonja de Groot, Lucas H V van der Woude   +4 more
doaj   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source