Results 91 to 100 of about 183,167 (316)

Balancing latency and availability in geo-distributed cloud data stores

open access: yes, 2013
Modern web applications face stringent requirements along many dimensions including latency, scalability, and availability. In response, several geo-distributed cloud storage systems have emerged in recent years.
Tawarmalani, Mohit   +3 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

A Review of Distributed Energy Storage System Solutions and Configurations for New Distribution Grids

open access: yes南方能源建设
[Introduction] With the advancement of the "dual carbon" goals and the introduction of new energy allocation and storage policies in various regions, there is a need to further clarify the role of distributed energy storage in the new types of ...
Haiquan HUANG   +7 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Managing very-large distributed datasets

open access: yes, 2008
In this paper, we introduce a system for handling very large datasets, which need to be stored across multiple computing sites. Data distribution introduces complex management issues, particularly as computing sites may make use of different storage ...
De Roure, David   +2 more
core  

Modeling of Hydro-Pneumatic Energy Storage Using Pump Turbines [PDF]

open access: yes, 2011
Modelling of a hydro-pneumatic energy storage system is presented in this paper. Hydro pneumatic storage aims to combine the good efficiency of hydraulic energy conversion and the space flexibility of pneumatic storage.
COLAS, Frédéric   +4 more
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

FutureGRID: A Program for long-term research into GRID systems architecture

open access: yes, 2008
This is a project to carry out research into long-term GRID architecture, in the University of Cambridge Computer Laboratory and the Cambridge eScience Center, with support from the Microsoft Research Laboratory, Cambridge.

core  

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