Results 81 to 90 of about 183,167 (316)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Autonomic management in a distributed storage system

, 2009
This thesis investigates the application of autonomic management to a distributed storage system. Effects on performance and resource consumption were measured in experiments, which were carried out in a local area test-bed.
Markus Tauber, Tauber, Markus
core  

Design, implementation and deployment of state machines using a generative approach

, 2008
We describe an approach to designing and implementing a distributed system as a family of related finite state machines, generated from a single abstract model.
Graham N. C. Kirby, Dearle, Alan, Alan Dearle, Kirby, Graham Njal Cameron, Norcross, Stuart John, Stuart J. Norcross   +5 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Research on Two-Stage Energy Storage Optimization Configurations of Rural Distributed Photovoltaic Clusters Considering the Local Consumption of New Energy

Energies
As photovoltaic technologies are being promoted throughout the country, the widespread installation of distributed photovoltaic systems in rural areas in rural regions compromises the safety and stability of the distribution network.
Yang Liu, Dawei Liu, Keyi Kang, Guanqing Wang, Yanzhao Rong, Weijun Wang, Siyu Liu   +6 more
doaj   +1 more source

Secure Secret Sharing With Adaptive Bandwidth in Distributed Cloud Storage Systems

IEEE Access, 2020
The development of cloud storage technology has brought us great convenience that we can store data in remote servers and access it on any connected device.
Hailiang Xiong, Changwu Hu, Yujun Li, Guangyuan Wang, Hongchao Zhou   +4 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Research on Grid-Forming Energy Storage Configuration for Distributed Photovoltaic Consumption and Reliability Improvement of Distribution Network [PDF]

Dianli jianshe
[Objective] High-penetration distributed photovoltaic（PV）grid integration leads to insufficient power absorption capacity in distribution networks. Meanwhile，the development of new distribution systems imposes higher reliability requirements.
XU Deyu, HUANG Yuan, TANG Zhiyuan, LIU Junyong, SUN Zengjie, HAO Zhifang
doaj   +1 more source

Policy architecture for distributed storage systems

, 2009
textDistributed data storage is a building block for many distributed systems such as mobile file systems, web service replication systems, enterprise file systems, etc.
Nalini Moti Belaramani, Belaramani, Nalini Moti   +1 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source