Results 161 to 170 of about 1,327,655 (368)

Long Short-Term Renewable Energy Sources Prediction for Grid-Management Systems Based on Stacking Ensemble Model

Energies
The transition towards sustainable energy systems necessitates effective management of renewable energy sources alongside conventional grid infrastructure.
Wiem Fekih Hassen, Maher Challouf
doaj   +1 more source

Towards more effective testing of communications-critical large scale systems [PDF]

, 2014
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.A publication based on the research from this thesis has been published and can be cited as Nabulsi, MA and Hierons, RM (2014), A new test framework for ...
Nabulsi, Mohammad
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

A comparison of distributed data parallel multimedia computing over conventional and optical wide-area networks

, 2008
The research area of Multimedia Content Analysis (MMCA) considers all aspects of the automated extraction of knowledge from multimedia data streams and archives.
Seinstra, F.J., Liu, F.
core  

Performance analysis of object-oriented designs for distributed systems [PDF]

, 1999
Performance is an important but often overlooked aspect of systems design. As a consequence, deployed software systems can fail to satisfy requirements and frequently disappoint customers and users. Successful systems are often achieved more by trial and
Utton, Peter, Martin, Gino, Waters, A. Gill, Akehurst, David H.   +3 more
core  

Brain-derived neurotrophic factor-like immunoreactivity in the adult rat central nervous system predominantly distributed in neurons with substantial amounts of brain-derived neurotrophic factor messenger RNA or responsiveness to brain-derived neurotrophic factor [PDF]

, 1997
Seishi Furukawa, Yuji Sugihara, F Iwasaki, Hidefumi Fukumitsu, Atsumi Nitta, Hiroshi Nomoto, Yoshiko Furukawa   +6 more
openalex   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Comparing conventional and distributed approaches to simulation in complex supply-chain health systems

, 2007
Decision making in modern supply chains can be extremely daunting due to their complex nature. Discrete-event simulation is a technique that can support decision making by providing what-if analysis and evaluation of quantitative data. However, modelling
Mustafee, N, Katsaliaki, K, Taylor, SJE, Brailsford, S   +3 more
core