Results 141 to 150 of about 11,258,293 (306)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Design and Verification of Distributed Multi-media Systems [PDF]

open access: yes
Performance analysis of computing systems, in particular distributed computing systems, is a complex process. Analysing the complex flows and interactions between a set of distributed processing nodes is a non-trivial task.
Derrick, John   +2 more
core  

Information Bottleneck Classification in Extremely Distributed Systems. [PDF]

open access: yesEntropy (Basel), 2020
Ullmann D   +5 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Communications And Distributed Systems Support For Multimedia

open access: yes, 2007
INTRODUCTION A wide variety of application areas have been identified for the emerging field of distributed multimedia systems. These include office information systems, scientific collaboration, conferencing systems and distance learning.
Doug Shepherd, Doug Shepherd Distributed
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Lightweight WebAssembly-Based Intrusion Detection for Zero Trust Edge Networks

open access: yesIEEE Access
IoT devices deployed across computing continuum infrastructures present significant security challenges due to resource constraints and decentralization. Traditional centralized intrusion detection systems struggle in such environments because of limited
Jonathan Weber   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

System design for distributed adaptive observation systems

open access: yes, 2011
Currently, there is no clear-cut approach or design methodology available for designing distributed adaptive observation systems, partly due to the necessity to combine elements and approaches from several technological and scientific communities ...
Ditzel, M.   +2 more
core  

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