Results 111 to 120 of about 23,134,989 (378)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

Nitrogen distribution by globin [PDF]

, 1923
This and other experiences with the tryptophane method of Fürth and Nobel led us to doubt seriously the reliability of quantitative data obtained by its application.
Borsook, Henry, Hunter, Andrew
core  

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source

Dynamic Equivalent Modeling of a Grid-Tied Microgrid Based on Characteristic Model and Measurement Data

Energies, 2017
Microgrids can significantly improve the utilization of distributed generation (DG) and the reliability of the power supply. However, in the grid-tied operational mode, the interaction between the microgrid and the distribution network cannot be ignored.
Changchun Cai, Haolin Liu, Weili Dai, Zhixiang Deng, Jianyong Zhang, Lihua Deng   +5 more
doaj   +1 more source

Quantum cryptography: Public key distribution and coin tossing [PDF]

Theoretical Computer Science, 2014
Charles H. Bennett, Gilles Brassard
semanticscholar   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

A Novel State of Charge Estimation Method Based on Electrochemical Impedance Spectroscopy for Solid-State Batteries of Next-Generation Space Power Sources under Different States of Health

Space: Science & Technology
With the increasing demand for battery energy density and safety, solid-state batteries are expected to become one of the ideal energy storage devices. Aiming at compensating for the research lack of modeling and state estimation of solid-state batteries,
Bingxiang Sun, Junfeng Pang, Liying Zhu, Xinze Zhao, Weige Zhang, Shichang Ma, Xiaopeng Liu   +6 more
doaj   +1 more source

An MILP approach for detailed scheduling of oil depots along a multi-product pipeline

Petroleum Science, 2017
Oil depots along products pipelines are important components of the pipeline transportation system and down-stream markets. The operating costs of oil depots account for a large proportion of the total system’s operating costs.
Hao-Ran Zhang, Yong-Tu Liang, Qi Liao, Jing Ma, Xiao-Han Yan   +4 more
doaj   +1 more source