Results 61 to 70 of about 2,480,489 (289)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The NSCT-HMT Model of Remote Sensing Image Based on Gaussian-Cauchy Mixture Distribution

IEEE Access, 2018
The nonsubsampled Contourlet transform (NSCT) not only retains the characteristics of Contourlet transform, but also has the good characteristic of shift-invariance, which plays a significant role in denoising, fusion, and segmentation of texture-rich ...
Xianghai Wang, Ruoxi Song, Chuanming Song, Jingzhe Tao   +3 more
doaj   +1 more source

An Overview of Composite Standard Elastic-Net Distribution Based on Complex Wavelet Coefficients

Journal of Mathematics, 2022
Statistical tools have changed significantly in the past decade; when the maximum likelihood method is usually applied, it provides an inaccurate solution due to its unsuitable properties and causes problems in fit.
Tahani A. Aloafi, Hassan M. Aljohani
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Thermodynamics of As, Sb and Bi distribution during reverb furnace smelting [PDF]

Journal of Mining and Metallurgy. Section B: Metallurgy, 2002
The results of thermodynamic analysis of arsenic, antimony and bismuth distribution between copper matte and discard slag in reverberatory smelting at 1573 K are shown in this paper.
Mitevska N., Živković Živan D.
doaj   +1 more source

The distribution of Mahler's measures of reciprocal polynomials

, 2003
We study the distribution of Mahler's measures of reciprocal polynomials with complex coefficients and bounded even degree. We discover that the distribution function associated to Mahler's measure restricted to monic reciprocal polynomials is a ...
Sinclair, Christopher D.
core   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Transport coefficients in modified Kappa distributed plasmas [PDF]

Annales Geophysicae
This work derives transport coefficients, i.e., electrical conductivity, thermoelectric, diffusion, and mobility coefficients, for a Lorentz plasma with a modified Kappa distribution.
M. J. Jwailes, I. A. Barghouthi, Q. S. Atawnah   +2 more
doaj   +1 more source

Measuring the through-plane and in-plane oxygen apparent diffusion coefficients in the gas diffusion layer

Frontiers in Energy Research, 2023
Accurately predicting oxygen mass transport resistance and current distribution in fuel cells requires significant knowledge of oxygen diffusion coefficients in both in-plane and through-plane directions.
Keguang Yao, Keguang Yao, Tiehan Long, Yajun Wang, Xiao-Zi Yuan, Yao Yao, Haijiang Wang, Haijiang Wang   +7 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source