Results 91 to 100 of about 12,478,031 (344)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Ripple Signaling Control for Ancillary Services in Distribution Networks

open access: yesTurkish Journal of Electrical Power and Energy Systems, 2022
Evangelos Boutsiadis   +2 more
doaj   +1 more source

Topological Taxonomy of Water Distribution Networks

open access: yes, 2018
Water Distribution Networks (WDNs) can be regarded as complex networks and modeled as graphs. In this paper, Complex Network Theory is applied to characterize the behavior of WDNs from a topological point of view, reviewing some basic metrics, exploring ...
C. Giudicianni   +5 more
semanticscholar   +1 more source

Distributed Quantization Networks

open access: yes, 2012
Several key results in distributed source coding offer the intuition that little improvement in compression can be gained from intersensor communication when the information is coded in long blocks. However, when sensors are restricted to code their observations in small blocks (e.g., 1), intelligent collaboration between sensors can greatly reduce ...
Sun, John Z., Goyal, Vivek K.
openaire   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy