Results 111 to 120 of about 15,786,892 (337)

Component sizes in networks with arbitrary degree distributions

, 2007
We give an exact solution for the complete distribution of component sizes in random networks with arbitrary degree distributions. The solution tells us the probability that a randomly chosen node belongs to a component of size s, for any s. We apply our
M. E. J. Newman, M. E. J. Newman, P. Erdős   +2 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Dynamic reconfiguration of three-phase unbalanced distribution networks

International Journal of Electrical Power & Energy Systems, 2018
The increasing penetration of distributed generations (DGs) and variable loads introduces significant power fluctuations to distribution networks, rendering conventional reconfiguration strategies ineffective.
H. Zhai, Ming Yang, Bo Chen, N. Kang
semanticscholar   +1 more source

Transition from fractal to non-fractal scalings in growing scale-free networks

, 2008
Real networks can be classified into two categories: fractal networks and non-fractal networks. Here we introduce a unifying model for the two types of networks. Our model network is governed by a parameter $q$.
A. Fronczak, A.-L. Barabási, C. Song, C. Song, C.-M. Ghima, C.L. Freeman, C.P. Massen, D.J. Watts, E. Bollt, H.D. Rozenfeld, H.D. Rozenfeld, Jihong Guan, K. Klemm, K.-I. Goh, L.A. Braunstein, L.da.F. Costa, Lichao Chen, M. Hinczewski, M. Hinczewski, M. Kitsak, M.E.J. Newman, M.E.J. Newman, M.E.J. Newman, P. Erdös, R. Albert, S. Boccaletti, S. Jung, S.N. Dorogovtsev, Shuigeng Zhou, Z.Z. Zhang, Zhongzhi Zhang   +30 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Three‐phase four‐wire power flow solution for multi‐grounded distribution networks with non‐bolted grounding

IET Generation, Transmission & Distribution
This study proposes a direct ZBUS three‐phase four‐wire power flow method to accurately analyse the neutral line and multiple grounding characteristics.
Nien‐Che Yang, Song‐Ting Zeng
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Ripple Signaling Control for Ancillary Services in Distribution Networks

Turkish Journal of Electrical Power and Energy Systems, 2022
Evangelos Boutsiadis, Dimitrios Tsiamitros, Dimitrios Stimoniaris   +2 more
doaj   +1 more source