Results 121 to 130 of about 878,815 (369)

Distributed Paging for General Networks

open access: yesJournal of Algorithms, 1998
Summary: Distributed paging deals with the dynamic allocation of copies of files in a distributed network as to minimize the total communication cost over a sequence of read and write requests. Most previous work deals with the file allocation problem, where infinite nodal memory capacity is assumed. In contrast the distributed paging problem makes the
Baruch Awerbuch, Yair Bartal, Amos Fiat
openaire   +3 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Distributed consensus in resilient networks

open access: yes2017 IEEE 56th Annual Conference on Decision and Control (CDC), 2017
In this paper, we investigate the necessary and sufficient conditions on the network for non-faulty nodes to reach consensus using only local information in the presence of structured Byzantine (StrBYZ) faulty agents. After presenting a new fault model classification, we carry out the analysis not only on the original network but also on the expanded ...
Halil Yigit Öksüz, Mehmet Akar
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Reference Models and Incentive Regulation of Electricity Distribution Networks: An Evaluation of Sweden’s Network Performance Assessment Model (NPAM)

open access: yes, 2007
The world-wide electricity sector reforms have led to a search for alternative and innovative approaches to regulation to promote efficiency improvement in the natural monopoly electricity networks.
Pollitt, Michael, Jamasb, Tooraj
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Improvement of 6/10 kV Distribution Power Networks Efficiency

open access: yes, 2018
The study focuses on the ways to improve the operation efficiency of 6 kV and 10 kV distribution power networks on the example of the Horodok District Power Network, Lvivoblenergo PJSC (Ukraine).
Zinoviy Bakhor   +3 more
core   +1 more source

Distributed Corruption Detection in Networks

open access: yesTheory Comput., 2015
We consider the problem of distributed corruption detection in networks. In this model, each vertex of a directed graph is either truthful or corrupt. Each vertex reports the type (truthful or corrupt) of each of its outneighbors. If it is truthful, it reports the truth, whereas if it is corrupt, it reports adversarially.
Alon, N, Mossel, E, Pemantle, R
openaire   +3 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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