Results 121 to 130 of about 7,631,256 (302)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

A simple model to characterize social networks

, 2012
For the purpose of prediction analysis of customer relationships in social networks, this paper proposes a simple model that can generate future states of a social network based on relevant data analysis.
Zeng, R., Hong Shen, Xu, T., Tian Wei Xu, Shen, H., Rui Zeng   +5 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

A multi-grade reactive power utilization evaluation method for distribution networks with high renewables

Frontiers in Energy Research
This paper proposes a multi-grade reactive power utilization evaluation strategy for distribution networks with high renewables to identify the devices with low-grade utilization efficiency.
Min Xu, Wenqian Yao, Wanyan Zeng, Tianting Li, Zhou Wang, Qing Dou   +5 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

The Spatial Structure of Production/Distribution Networks and Its Implication for Technology Transfers and Spillovers [PDF]

This paper argues that a variety of firm specificity supported by sophisticated inter-firm relationships is essential for understanding the mechanics and spatial structure of international production/distribution networks in East Asia. By mapping the two-
Fukunari KIMURA
core  

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

A two‐stage reactive power optimization method for distribution networks based on a hybrid model and data‐driven approach

IET Renewable Power Generation
The uncertainty of distributed energy resources (DERs) and loads in distribution networks poses challenges for reactive power optimization and control timeliness.
Ghulam Abbas, Wu Zhi, Aamir Ali
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Multi‐objective multiperiod stable environmental economic power dispatch considering probabilistic wind and solar PV generation

IET Renewable Power Generation
The economic‐environmental power dispatch (EEPD) problem, a widely studied bi‐objective non‐linear optimization challenge in power systems, traditionally focuses on the economic dispatch of thermal generators without considering network security ...
Aamir Ali, Sumbal Aslam, Sohrab Mirsaeidi, Noor Hussain Mugheri, Riaz Hussain Memon, Ghulam Abbas, Hammad Alnuman   +6 more
doaj   +1 more source