Results 131 to 140 of about 12,478,031 (344)

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

A two‐stage reactive power optimization method for distribution networks based on a hybrid model and data‐driven approach

open access: yesIET Renewable Power Generation
The uncertainty of distributed energy resources (DERs) and loads in distribution networks poses challenges for reactive power optimization and control timeliness.
Ghulam Abbas, Wu Zhi, Aamir Ali
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Multi‐objective multiperiod stable environmental economic power dispatch considering probabilistic wind and solar PV generation

open access: yesIET Renewable Power Generation
The economic‐environmental power dispatch (EEPD) problem, a widely studied bi‐objective non‐linear optimization challenge in power systems, traditionally focuses on the economic dispatch of thermal generators without considering network security ...
Aamir Ali   +6 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

A distributed photovoltaic short‐term power forecasting model based on lightweight AI for edge computing in low‐voltage distribution network

open access: yesIET Renewable Power Generation
Recent years, the tremendous number of distributed photovoltaic are integrated into low‐voltage distribution network, generating a significant amount of operational data.
Yuanliang Fan   +7 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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