Results 91 to 100 of about 76,351 (297)

The Evolution of Equid Monodactyly: A Review Including a New Hypothesis

Frontiers in Ecology and Evolution, 2019
The traditional story of horse evolution is well-known: over time, horses became larger, they attained higher-crowned teeth, and they changed from having three toes (tridactyly) to a single toe (monodactyly). Evolution is often perceived as a progression
Christine M. Janis, Christine M. Janis, Raymond L. Bernor   +2 more
doaj   +1 more source

Chaotic Distribution of Prime Numbers and Digits of π

SSRN Electronic Journal, 2020
3 pages, 8 figures.
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Large sieve inequalities for exceptional Maass forms and the greatest prime factor of $n^2+1$

Forum of Mathematics, Pi
We prove new large sieve inequalities for the Fourier coefficients $\rho _{j\mathfrak {a}}(n)$ of exceptional Maass forms of a given level, weighted by sequences $(a_n)$ with sparse Fourier transforms – including two key types of sequences ...
Alexandru Pascadi
doaj   +1 more source

Actinomyces spp. gene expression in root caries lesions

Journal of Oral Microbiology, 2016
Background: The studies of the distribution of Actinomyces spp. on carious and non-carious root surfaces have not been able to confirm the association of these bacteria with root caries, although they were extensively implicated as a prime suspect in ...
Naile Dame-Teixeira, Clarissa Cavalcanti Fatturi Parolo, Marisa Maltz, Aradhna Tugnait, Deirdre Devine, Thuy Do   +5 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Eigenvalues of diffusion operators and Prime numbers

, 2017
In this paper, the relationship between the positive eigenvalues ofdiffusion operators and prime numbers is investigated. We also propose a Sturm-Liouvilleproblem with Coulomb singularity that shows eigenvalues the distribution ofprime ...
İbrahim Adalar, Adalar, İbrahim, Amirov, Rauf, Rauf Amirov   +3 more
core   +2 more sources

Shaping of Natural Killer Cell Antitumor Activity by Ex Vivo Cultivation

Frontiers in Immunology, 2017
Natural killer (NK) cells are a promising tool for the use in adoptive immunotherapy, since they efficiently recognize and kill tumor cells. In this context, ex vivo cultivation is an attractive option to increase NK cells in numbers and to improve their
Markus Granzin, Evelyn Ullrich, Evelyn Ullrich, Juliane Wagner, Juliane Wagner, Ulrike Köhl, Adelheid Cerwenka, Adelheid Cerwenka, Volker Huppert   +8 more
doaj   +1 more source

DISTRIBUTION OF PRIME AND COMPOSITE NUMBERS AND THEIR ALGORHYTHMIC APPENDICES

, 2017
The article focuses on methods defining and distributing the composite numbers, prime numbers, twins of prime numbers and composite numbers of twins that do not have divisors 2 and 3 in N , based on the set of numbers of type Θ = {6 k ± 1 / kN } where N ...
Sergey Ivanovich Chermidov
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source