Results 101 to 110 of about 633,827 (270)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Universal characteristics of fractal fluctuations in prime number distribution [PDF]
International Journal of General Systems, 2014 35 pages, 11 ...
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Discrepancies in the distribution of prime numbers
Journal of Number Theory, 1982 AbstractChebyshev has noticed a certain predominance of primes of the form 4n + 3 over those of the form 4n + 1. He asserted that limx→∞∑p > 2 (−1)(p − 1)2e−px = −∞. This was unproven until today. G. H. Hardy, J. E. Littlewood and E. Landau have shown its equivalence with an analogue to the famous Riemann hypothesis, namely, L(s, χ1mod 4) ≠ 0, Re(s ...
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Beyond Expansion IV: Traces of Thin Semigroups
Discrete Analysis, 2018 Beyond Expansion IV: Traces of Thin Semigroups, Discrete Analysis 2018:6, 27 pp. This is the fourth in a series of papers by Bourgain and Kontorovich that study the arithmetic properties of groups and semigroups of 2-by-2 integer matrices.
Jean Bourgain, Alex Kontorovich
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
About the Distribution of Prime Numbers
, 2017 In this article, a prime number distribution formula is given. The formula is based on the periodic property of the sine function and an important trigonometric limit.
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