Results 91 to 100 of about 3,209,718 (264)

Stabilizing buried interface by bilateral bond strength equilibrium strategy toward efficient perovskite photovoltaics

Nature Communications
The NiOx/perovskite interface in p-i-n inverted perovskite solar cells (PSCs) suffers from trap-assisted nonradiative recombination, chemical reactions and weak adhesion.
Jike Ding, Yunxiao Liao, Hao Liu, Yong Ding, Quanxing Ma, Mengjia Li, Zuoling Zhang, Jiajia Zhang, Jian-Xin Tang, Jiang Sheng, Jiangzhao Chen, Cong Chen   +11 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

An optimal expansion planning of electric distribution network incorporating health index and non-network solutions

CSEE Journal of Power and Energy Systems, 2020
Limei Zhou, Wanxing Sheng, Wei Liu, Zhao Ma   +3 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

A Novel State of Charge Estimation Method Based on Electrochemical Impedance Spectroscopy for Solid-State Batteries of Next-Generation Space Power Sources under Different States of Health

Space: Science & Technology
With the increasing demand for battery energy density and safety, solid-state batteries are expected to become one of the ideal energy storage devices. Aiming at compensating for the research lack of modeling and state estimation of solid-state batteries,
Bingxiang Sun, Junfeng Pang, Liying Zhu, Xinze Zhao, Weige Zhang, Shichang Ma, Xiaopeng Liu   +6 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Operational Feasible Region of Active Distribution Networks Based on the Holomorphic Embedding Method

Energies
With the increasing penetration of distributed energy resources (DERs) in distribution networks, voltage stability issues are becoming increasingly prominent, making the accurate characterization of the system’s security boundaries crucial.
Jiarui Wang, Jiajun Zhang, Haitao Lan, Haifeng Zhang, Guicheng Zhang, Shihan Chen, Fengzhang Luo, Ranfeng Mu   +7 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Finite Element Modelling Method and Dynamic Characteristics of the Revolute Joints of a Simply Supported Bar During Dynamic Buckling

Shock and Vibration
The explicit dynamic finite element method (FEM) has been successfully employed for simulating the buckling response of beam or bar structures under axial impact.
Sai Liu, Weigui Zhang
doaj   +1 more source