Results 101 to 110 of about 7,323,442 (275)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A Novel Hypothesis Testing-Based Scheme for Root Cause Classification of Disturbances in Distribution Systems

IEEE Open Access Journal of Power and Energy
In power systems, disturbances often result from faults or operational events, making it crucial to accurately identify their sources to prevent system failures and maintain grid stability.
Xiao Zhang, Hao Liang, Yindi Jing
doaj   +1 more source

Internet of Things-aided Smart Grid: Technologies, Architectures, Applications, Prototypes, and Future Research Directions

, 2019
Traditional power grids are being transformed into Smart Grids (SGs) to address the issues in existing power system due to uni-directional information flow, energy wastage, growing energy demand, reliability and security.
Copeland, Rebecca, Crespi, Noel, Rehmani, Mubashir Husain, Saleem, Yasir   +3 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Reactive Power Management Considering Stochastic Optimization under the Portuguese Reactive Power Policy Applied to DER in Distribution Networks

Energies, 2019
Challenges in the coordination between the transmission system operator (TSO) and the distribution system operator (DSO) have risen continuously with the integration of distributed energy resources (DER).
Tiago Abreu, Tiago Soares, Leonel Carvalho, Hugo Morais, Tiago Simão, Miguel Louro   +5 more
doaj   +1 more source

Elements for Response Time Statistics in ERP Transaction Systems

, 2005
We present some measurements and ideas for response time statistics in ERP systems. It is shown that the response time distribution of a given transaction in a given system is generically a log-normal distribution or, in some situations, a sum of two or ...
Abramowitz, Andreas Mielke, Arlitt, Au-Yeung, Karian, Paxson, Risken, Schneider, Sole, Trivedi, Willinger   +10 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

A linear distribution of orbits in compact planetary systems?

, 2013
We report a linear ordering of orbits in a sample of multiple extrasolar planetary systems with super-Earth planets. We selected 20 cases, mostly discovered by the Kepler mission, hosting at least four planets within \sim 0.5 au.
Gozdziewski, Krzysztof, Migaszewski, Cezary, Slonina, Mariusz   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source