Results 131 to 140 of about 2,335,988 (318)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Experimental Investigation and Evaluation of Future Active Distribution Networks [PDF]

, 2010
The UK government’s policy to achieve a 20% renewable energy generation target by 2020, will require significant amounts of SSEG (Small-Scale Embedded Generation) to be connected.
Lyons, Padraig Fionnbharr, LYONS, PADRAIG,FIONNBHARR   +1 more
core  

Design of Step Voltage Regulator Based on IGBT

Energies
The introduction of distributed generation (DG) into distribution systems is expanding due to carbon neutral policies. DG with intermittent output characteristics brings frequent voltage variations in distribution systems.
Min-Gu Lee, Jong-Bin Kim, Kwang-Jae Park, Ju-Won Song, Ye-Jung Kim, Jae-Eon Kim   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dynamic power distribution management for all electric aircraft [PDF]

, 2011
In recent years, with the rapid development of electric and electronic technology, the All-Electric Aircraft (AEA) concept has attracted more and more attention, which only utilizes the electric power instead of conventional hydraulic and pneumatic ...
Xia, Xiuxian
core  

Seamless pressure-deficient water distribution system model

, 2010
Pressure-deficient conditions are a common occurrence in water distribution systems. These situations require accurate modelling for timely decision making.
Tanyimboh, Tiku, Templeman, AB, A. B. Templeman, T. T. Tanyimboh   +3 more
core   +1 more source

Classification methodology and feature selection to assist fault location in power distribution systems

Revista Facultad de Ingeniería Universidad de Antioquia, 2008
A classification methodology based on Support Vector Machines (SVM) is proposed to locate the faulted zone in power distribution networks. The goal is to reduce the multiple-estimation problem inherent in those methods that use single end measures (in ...
Juan José Mora Flórez, Germán Morales España, Sandra Pérez Londoño   +2 more
doaj  

Distributed Cognition in the Age of Distributed Systems.

, 2015
In parallel with the development of the theory of distributed cognition, the study of distributed computing has progressed rapidly. This research has both been driven by pragmatic insights into the practicalities of coordinating computational processes and resulted in formal theories of distributed systems.
Soutar-Rau, Ethan, Fisher, Brian
openaire   +1 more source