Results 61 to 70 of about 247,502 (280)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Configurations, Power Topologies and Applications of Hybrid Distribution Transformers

Energies, 2021
Distribution systems are under constant stress due to their highly variable operating conditions, which jeopardize distribution transformers and lines, degrading the end-user service.
Alvaro Carreno, Marcelo Perez, Carlos Baier, Alex Huang, Sanjay Rajendran, Mariusz Malinowski   +5 more
doaj   +1 more source

Optimal passive filter design for effective utilization of cables and transformers under non-sinusoidal conditions [PDF]

, 2014
Transformers and cables have overheating and reduced loading capabilities under non-sinusoidal conditions due to the fact that their losses increases with not only rms value but also frequency of the load current.
Aleem, SHEA, Balci, ME, Sakar, S, Zobaa, AF   +3 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Efficient Strategy for Distribution Transformer Replacement: A Study on Replacement Methods in Power Systems

Jurnal ELTIKOM: Jurnal Teknik Elektro, Teknologi Informasi dan Komputer
A dependable and efficient electric power distribution system is increasingly required due to growing industrial and population demand. Many distribution transformers currently in use are outdated, which increases operating expenses and reduces ...
Nur Asmi Rahmawati
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Online capacity detection of distribution transformers based on zero-sequence impedance curve matching

Frontiers in Energy Research
Unauthorized tampering with distribution transformer nameplates poses significant economic and operational risks to power utilities, while conventional offline capacity detection methods require power outages and existing online short-circuit impedance ...
Bo Li, Yu-Xing Lei, Meng-Meng Zhu, Yao-Hua Liao, Ren-Jie Guo, Ming-Gui Yang, Xin-Dong Zhang   +6 more
doaj   +1 more source

Temperature Distribution in Core and Winding of a Transformer and Its Effect on Performance

Wasit Journal of Engineering Sciences, 2016
In order to reach the maximum power from a transformer and avoid thermal accidents, it is essential to carefully study its thermal behavior. This research is to apply some computational and analytical approaches in order to obtain a temperature ...
Mahmmod Aziz Muhammed, Abdul Ridha Ghedayer   +1 more
doaj   +1 more source

Economic criteria for optimizing the number and load factor of mining transformers [PDF]

, 2019
Purpose. This article discusses how to choose the optimal number and load factor, respectively the economic power in the first year of mining power transformers operation. The analysis is carried out based on technical-economic criteria.
Deliu, F, Pana, L, Pasculescu, D, Pasculescu, V.M.   +3 more
core   +1 more source