Results 61 to 70 of about 250,902 (302)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Nowadays, the quality of electrical energy really needs to be improved especially for industrial purposes that require a good level of reliability in the distribution of electrical energy.
Brainvendra Widi Dionova +3 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Configurations, Power Topologies and Applications of Hybrid Distribution Transformers
Distribution systems are under constant stress due to their highly variable operating conditions, which jeopardize distribution transformers and lines, degrading the end-user service.
Alvaro Carreno +5 more
doaj +1 more source
Optimal passive filter design for effective utilization of cables and transformers under non-sinusoidal conditions [PDF]
Transformers and cables have overheating and reduced loading capabilities under non-sinusoidal conditions due to the fact that their losses increases with not only rms value but also frequency of the load current.
Aleem, SHEA +3 more
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Embedded intelligence for electrical network operation and control [PDF]
Integrating multiple types of intelligent, mulitagent data analysis within a smart grid can pave the way for flexible, extensible, and robust solutions to power network ...
Catterson, Victoria +2 more
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
A dependable and efficient electric power distribution system is increasingly required due to growing industrial and population demand. Many distribution transformers currently in use are outdated, which increases operating expenses and reduces ...
Nur Asmi Rahmawati
doaj +1 more source

