Results 41 to 50 of about 2,224 (245)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Environmental Research: EnergyNearshoring is reshaping Mexico’s industrial geography and electricity demand, creating opportunities for growth while raising energy-justice concerns over who benefits, who pays, and whose needs are recognized. This study synthesizes policy evidence and
Citlaly Pérez-Briceño +6 more
doaj +1 more source
Motivational and Ideological Underpinnings of Welfare Preferences in Eastern and Western Europe
Europe's Journal of Psychology, 2016 In our study we investigated the motivational and ideological correlates of the approval of welfare services in postsocialist Central Eastern and Western Europe.
Márton Hadarics
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Justice can and should become a part of feasibility assessments for climate mitigation policies
npj Climate ActionConcerns of justice are rarely considered within feasibility assessments of climate mitigation policies, even when present conditions and climate action itself have serious implications for vulnerable populations, potentially undermining the desirability
Maitreyee Sevekari +3 more
doaj +1 more source
Employee engagement and remuneration justice in Lithuania and Poland
Business: Theory and Practice, 2020 The aim of the article is the analysis of the relationship between work engagement and evaluation of remuneration justice in the context of the dimensions of organizational justice in Lithuania and Poland.
Marta Juchnowicz +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Some Highlights on the Concept of Environmental Justice and its Use
e-cadernos ces, 2012 The article provides a review of the literature on environmental justice, aimed at showing the multifaceted character of the concept and how it has been used since the mid-80s, with special reference to its shift across the Atlantic and over time.
Ilaria Beretta
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source