Results 131 to 140 of about 9,044 (253)

Learning Optimal Distributionally Robust Individualized Treatment Rules. [PDF]

J Am Stat Assoc, 2021
Mo W, Qi Z, Liu Y.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A Distributionally Robust Optimization Method for Passenger Flow Control Strategy and Train Scheduling on an Urban Rail Transit Line. [PDF]

Engineering (Beijing), 2022
Lu Y, Yang L, Yang K, Gao Z, Zhou H, Meng F, Qi J.   +6 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Distributionally Robust Federated Learning With Client Drift Minimization

IEEE Transactions on Machine Learning in Communications and Networking
Federated learning (FL) faces critical challenges, particularly in heterogeneous environments where non-independent and identically distributed (non-IID) data across clients can lead to unfair and inefficient model performance. We introduce DRDM, a novel
Mounssif Krouka, Chaouki Ben Issaid, Mehdi Bennis   +2 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Carbon-aware mobile energy storage system scheduling in active power distribution systems under PV and traffic uncertainties

Energy Reports
Carbon emission flow (CEF) is a promising approach for assessing both generation-and consumption-side carbon footprints in the power system sector. In this study, we propose a carbon-aware mobile energy storage system (MESS) scheduling framework that ...
Panggah Prabawa, Dae-Hyun Choi
doaj   +1 more source

Distributionally Robust Kalman Filter

In this work, we propose a noise-centric formulation of the distributionally robust Kalman filter (DRKF) for discrete-time linear stochastic systems with uncertain noise statistics. By placing Wasserstein ambiguity sets directly on the process and measurement noise distributions, the proposed DRKF preserves the analytical structure of the classical ...
Jang, Minhyuk, Hakobyan, Astghik, Yang, Insoon   +2 more
openaire   +2 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Distributionally Robust Variational Quantum Algorithms With Shifted Noise

IEEE Transactions on Quantum Engineering
Given their potential to demonstrate near-term quantum advantage, variational quantum algorithms (VQAs) have been extensively studied. Although numerous techniques have been developed for VQA parameter optimization, it remains a significant challenge.
Zichang He, Bo Peng, Yuri Alexeev, Zheng Zhang   +3 more
doaj   +1 more source