Results 41 to 50 of about 3,143,268 (283)

Cooperative Operation Optimization for Multi-region Hydrogen-Integrated Integrated Energy System Based on Hybrid Wasserstein Two-Stage Distributionally Robust

open access: yesZhongguo dianli
An integrated energy system (IES) coupled with hydrogen energy is significantly influenced by source-load uncertainties when operating alone. Traditional robust optimization techniques are overly conservative, which impedes the economic performance.
Xiaoqiang DING, Zhi YUAN, Ji LI
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz   +12 more
wiley   +1 more source

Optimistic Distributionally Robust Policy Optimization

open access: yesCoRR, 2020
Trust Region Policy Optimization (TRPO) and Proximal Policy Optimization (PPO), as the widely employed policy based reinforcement learning (RL) methods, are prone to converge to a sub-optimal solution as they limit the policy representation to a particular parametric distribution class.
Jun Song, Chaoyue Zhao
openaire   +2 more sources

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Cardinality-constrained distributionally robust portfolio optimization

open access: yesEuropean Journal of Operational Research, 2023
This paper studies a distributionally robust portfolio optimization model with a cardinality constraint for limiting the number of invested assets. We formulate this model as a mixed-integer semidefinite optimization (MISDO) problem by means of the moment-based ambiguity set of probability distributions of asset returns.
Ken Kobayashi   +2 more
openaire   +4 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Optimization Scheduling of Integrated Energy Systems Considering Power Flow Constraints

open access: yesEnergies
To further investigate the complementary characteristics among subsystems of the combined electricity–gas–heat system (CEGHS) and to enhance the renewable energy accommodation capability, this study proposes a comprehensive optimization scheduling ...
Sheng Zou   +4 more
doaj   +1 more source

Distributionally Robust Optimization with Moment Ambiguity Sets

open access: yesJournal of Scientific Computing, 2022
AbstractThis paper studies distributionally robust optimization (DRO) when the ambiguity set is given by moments for the distributions. The objective and constraints are given by polynomials in decision variables. We reformulate the DRO with equivalent moment conic constraints.
Jiawang Nie   +3 more
openaire   +4 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Distributionally Robust Low-Carbon Scheduling Model for Virtual Power Plants Considering Emerging Distributed Resources and Electricity Carbon Trading [PDF]

open access: yesDianli jianshe
[Objective] To improve the low-carbon economic performance of scheduling strategies for virtual power plants, this study proposes a distributionally robust low-carbon scheduling model that incorporates emerging distributed resources and electricity ...
WANG Jiayi, HE Shuaijia
doaj   +1 more source

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