Results 61 to 70 of about 2,032 (302)

Distributionally Robust Optimization with Principal Component Analysis [PDF]

SIAM Journal on Optimization, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jianqiang Cheng, Richard Li-Yang Chen, Habib N. Najm, Ali Pinar, Cosmin Safta, Jean-Paul Watson   +5 more
openaire   +2 more sources

A hierarchical deep learning and distributionally robust framework for urban multi-energy systems

Results in Engineering
This paper presents a hierarchical optimization framework for distributed energy management in urban multi-energy systems that integrates deep learning-based forecasting with distributionally robust optimization.
Mohammad Heydari, Taher Niknam, Navid Parsa   +2 more
doaj   +1 more source

Bidding strategy for virtual power plants with the day-ahead and balancing markets using distributionally robust optimization approach

Energy Reports, 2023
Virtual power plant (VPP) coordinates the energy consumption or production of its components and trades power in both day-ahead market (DAM) and balancing market (BM) to maximize operating margins, where consists of intermittent distributed generation ...
Chunning Song, Xiping Jing
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Distributionally Robust Capacity Configuration for Energy Storage in Microgrid Considering Renewable Utilization

Frontiers in Energy Research, 2022
The energy storage plays an important role in the operation safety of the microgrid system. Appropriate capacity configuration of energy storage can improve the economy, safety, and renewable energy utilization of the microgrid.
Xin Ding, Hongyan Ma, Zheng Yan, Jie Xing, Jiatong Sun   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Direct Data-Driven Portfolio Optimization with Guaranteed Shortfall Probability [PDF]

, 2013
This paper proposes a novel methodology for optimal allocation of a portfolio of risky financial assets. Most existing methods that aim at compromising between portfolio performance (e.g., expected return) and its risk (e.g., volatility or shortfall ...
Calafiore, Giuseppe Carlo
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Distributionally robust optimization for sequential decision-making [PDF]

Optimization, 2019
The distributionally robust Markov Decision Process (MDP) approach asks for a distributionally robust policy that achieves the maximal expected total reward under the most adversarial distribution of uncertain parameters. In this paper, we study distributionally robust MDPs where ambiguity sets for the uncertain parameters are of a format that can ...
Zhi Chen, Pengqian Yu, William B. Haskell   +2 more
openaire   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source