Results 71 to 80 of about 6,626 (272)

Distributionally Robust Capacity Configuration for Energy Storage in Microgrid Considering Renewable Utilization

open access: yesFrontiers in Energy Research, 2022
The energy storage plays an important role in the operation safety of the microgrid system. Appropriate capacity configuration of energy storage can improve the economy, safety, and renewable energy utilization of the microgrid.
Xin Ding   +4 more
doaj   +1 more source

Calibration of Distributionally Robust Empirical Optimization Models [PDF]

open access: yesOperations Research, 2017
In “Calibration of Robust Empirical Optimization Models,” Gotoh, Kim, and Lim study the statistical properties of ɸ-divergence distributionally robust optimization with concave rewards. They show that worst-case sensitivity of the expected reward to deviations from the nominal is equal to the in-sample variance and that significant out-of-sample ...
Jun-ya Gotoh   +2 more
openaire   +4 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Distributionally robust optimization for sequential decision-making [PDF]

open access: yesOptimization, 2019
The distributionally robust Markov Decision Process (MDP) approach asks for a distributionally robust policy that achieves the maximal expected total reward under the most adversarial distribution of uncertain parameters. In this paper, we study distributionally robust MDPs where ambiguity sets for the uncertain parameters are of a format that can ...
Zhi Chen   +2 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Distributionally Robust Chance-Constrained Task Assignment for Heterogeneous UAVs with Time Windows Under Uncertain Fuel Consumption

open access: yesDrones
This paper addresses the cooperative task assignment problem for heterogeneous unmanned aerial vehicles with time windows considering uncertain fuel consumption. In the scenario where probabilistic fuel consumption exists and its distribution needs to be
Zhichao Gao   +4 more
doaj   +1 more source

Wasserstein Distributionally Robust Regret Optimization

open access: yesCoRR
Distributionally Robust Optimization (DRO) is a popular framework for decision-making under uncertainty, but its adversarial nature can lead to overly conservative solutions. To address this, we study ex-ante Distributionally Robust Regret Optimization (DRRO), focusing on Wasserstein-based ambiguity sets which are popular due to their links to ...
Lukas-Benedikt Fiechtner, Jose Blanchet
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Two-Stage Distributed Robust Air-Ground Cooperative Mission Planning: An Emergency Communication Solution for Addressing Probabilistic Uncertainty in Road Interruption

open access: yesFuture Internet
Earthquake disasters often cause communication base stations to fail, severely hindering rescue operations and information transmission. While traditional air-ground collaborative emergency communication systems can rapidly restore communications, they ...
Miao Miao, Wei Wang, Xiaokai Lian
doaj   +1 more source

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