Results 101 to 110 of about 9,886,252 (332)

fitdistrplus: An R Package for Fitting Distributions

open access: yes, 2015
The package fitdistrplus provides functions for fitting univariate distributions to different types of data (continuous censored or non-censored data and discrete data) and allowing different estimation methods (maximum likelihood, moment matching ...
M. Delignette-Muller, Christophe Dutang
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Aplicação dos sistemas de informação geográfica para definição de estratégias de manejo de bovinos nas pastagens Applying the geografic information systems to define cattle management of pastures

open access: yesRevista Brasileira de Zootecnia, 2007
O estudo de grandes áreas de pastejo, principalmente no que diz respeito ao seu uso pelos animais, é difícil, tanto na forma de amostragem, quanto na maneira de analisar os dados obtidos. Nesse contexto o Sistema de Informação Geográfica (SIG) surge como
Adriano Gomes Páscoa   +1 more
doaj   +1 more source

Identifying biotic determinants of historic American eel (Anguilla rostrata) distributions [PDF]

open access: yes, 2017
Traditionally, ecologists studying large scale patterns in species distributions emphasize abiotic variables over biotic interactions. Noting that both abiotic & biotic variables likely determine distributions of all organisms, many ecologists now aim ...
McGarvey, Daniel J, Woods, Taylor E
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Topology optimization for elastic base under rectangular plate subjected to moving load

open access: yesArchives of Control Sciences, 2015
Distribution optimization of elastic material under elastic isotropic rectangular thin plate subjected to concentrated moving load is investigated in the present paper. The aim of optimization is to damp its vibrations in finite (fixed) time.
Jilavyan Samvel H.   +1 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

HidroEsta, software for hydrological calculations

open access: yesTecnología en Marcha, 2016
This investigation, “HidroEsta, software for Hydrological Calculations” is oriented towards the creation of a computing tool using Visual Basic intended to facilitate and simplify difficult calculations that must be carried out in hydrological studies ...
Máximo Villón-Béjar
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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