Results 141 to 150 of about 2,246,072 (312)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Report of the Board of Commissioners of the District of Columbia, volume 2, 1902

open access: yes, 1902
Volume two of the report of the Board of Commissioners of the District of Columbia to Congress about government operations for the fiscal year ending June 30, 1902.
District of Columbia. Board of Commissioners District of Columbia. Engineer Departmentet al
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Report of the Board of Commissioners of the District of Columbia, volume 4, 1903

open access: yes, 1903
Volume 4 of the report of the Board of Commissioners of the District of Columbia to the President of the United States about government operations for the fiscal year ending June 30, 1903.
District of Columbia. Board of Commissioners District of Columbia. Board of Educationet al
core  

Gastronomic districts : a new kind of district

open access: yes, 2011
L’objet de cette thèse est d’expliquer la localisation de la gastronomie française à l’aide d’un concept de district gastronomique, en définissant celui-ci comme un type particulier de district industriel et / ou culturel. Après avoir construit la notion de district gastronomique, nous en étudions deux formes principales.En effet, nous identifions deux
openaire   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Report of the Board of Commissioners of the District of Columbia, volume 5, 1904

open access: yes, 1904
Volume five of the report of the Board of Commissioners of the District of Columbia to the President of the United States about government operations for the fiscal year ending June 30, 1904.
District of Columbia. Board of Commissioners District of Columbia. Department of Insuranceet al
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Finances of the District of Columbia, 1929

open access: yes, 1929
Reports of the Auditor, Assessor, and Collector of Taxes to the Board of Commissioners of the District of Columbia about public finances for the fiscal year ending June 30 ...
District of Columbia. Office of the Auditoret al
core  

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