Results 61 to 70 of about 4,619,412 (287)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
A comparison of prosumer system configurations in district heating networks
Energy Reports, 2021 Prosumer-based district heating networks attract an increasing interest in energy research. There are numerous publications addressing the prosumer integration into district heating networks with a focus on grid side operation.
Daniel Zinsmeister +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Efficient heat distribution in solar district heating systems
, 2018 This paper contains a short analysis showing the main benefit for solar district heating when a novel heat distribution concept with low temperatures is applied.
Werner, Sven, Averfalk, Helge
core +2 more sources
Flow patterns and heat transfer for flow boiling in small to micro diameter tubes [PDF]
, 2008 An overview of the recent developments in the study of flow patterns and boiling heat transfer in small to micro diameter tubes is presented. The latest results of a long-term study of flow boiling of R134a in five vertical stainless steel tubes of ...
Karayiannis, TG +3 more
core +5 more sources
Planning of heat supply of territories: model and algorithms
E3S Web of Conferences, 2018 The choice of direction of heat supply systems development in cities is an important task for the authorities, district heating companies and consumers.
Mednikova Ekaterina E.
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source