Results 81 to 90 of about 920,121 (365)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Do not disturb [PDF]

open access: yesQJM, 2006
The waiting room was clean and tidy but rather drab, and lacking in any friendly touches like paintings or historical photos. What particularly caught my attention were the notices on the walls and around the reception desk. ‘Don't consume food and drink, or chew gum in the waiting room.’ ‘Don't ask the doctors for housing letters as we do not issue ...
openaire   +2 more sources

Solent Disturbance and Mitigation Project Phase II: Predicting the impact of human disturbance on overwintering birds in the Solent.

open access: yes, 2012
The Solent coastline provides feeding grounds for internationally protected populations of overwintering waders and wildfowl, and is also extensively used for recreation.
West, Andrew D.   +3 more
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Interaction Diversity Maintains Resiliency in a Frequently Disturbed Ecosystem

open access: yesFrontiers in Ecology and Evolution, 2019
Frequently disturbed ecosystems are characterized by resilience to ecological disturbances. Longleaf pine ecosystems are not only resilient to frequent fire disturbance, but this feature sustains biodiversity.
Jane E. Dell   +8 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Dynamics at the treeline: differential responses of Picea mariana and Larix laricina to climate change in eastern subarctic Québec

open access: yesEnvironmental Research Letters, 2012
Treelines are known to be temperature-sensitive ecotones, and therefore could rapidly expand their range limits in response to climate warming. Observations of lack of range expansion, however, indicate that ecological constraints partly control the ...
Geneviève Dufour-Tremblay   +2 more
doaj   +1 more source

Assessing conservation of a tropical African estuary : waterbird disturbance, livelihoods, and ecotourism

open access: yes, 2011
The aim of this study was to evaluate the potential costs and benefits of increasing conservation in the Sabaki River Mouth Important Bird Area. This was achieved by assessing the vulnerability of waterbirds to disturbance from human activity in the ...
England, Kate
core  

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

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