Results 91 to 100 of about 576,419 (267)

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Plant–Soil Relationships Diminish Under Major Versus Moderate Climate Change in Subalpine Grasslands

open access: yesEcology and Evolution
Plant communities and soil microbial communities influence each other directly and indirectly via the resource pools they modify. Despite apparent sensitivities of plants and microbes to climate, little is known concerning how climate change will affect ...
Tyson J. Terry   +16 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

DISTURBED AND DISTURBING PASSENGERS

open access: yesDISTURBED AND DISTURBING PASSENGERS
Hollywood has shown an unending affection for the airplane for nearly one hundred years. From fantasy, to war, to salvation, to heroism, to romance, to adventure, airplanes have been and continue to be a powerful symbol in American film. Two intertwined themes based on flight are menace and hope, and the tension between them has successfully driven ...
openaire  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Robust adaptive backstepping control of H‐bridge inverter based on type‐2 fuzzy optimization of parameters

open access: yesIET Power Electronics
A type‐2 fuzzy logic‐based adaptive backstepping control (T2FABSC) approach is designed for an H‐bridge inverter. This inverter has an LC filter to decrease the level of total harmonic distortion (THD) that can affect the efficiency of the system ...
Hossein Azarinfar   +3 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Disruption of natural disturbance regime decouples habitat and life stage in a keystone species

open access: yesEcosphere
Anthropogenic disturbance of stream ecosystems, often chronic in nature, has been studied extensively. However, when disturbance is driven by more than one resource policy over many decades, feedback between habitat evolution and biological adaptation ...
Joseph E. Merz   +3 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Assessing uncertainty in forecasts of refugia for Joshua trees using high‐density distribution data

open access: yesEcosphere
Joshua trees (Yucca brevifolia and Yucca jaegeriana) are iconic, foundational species of the Mojave and Sonoran Deserts in North America. Due to their ecosystem importance, long generation times, and low resilience to disturbance, these hybridizing ...
Daniel F. Shryock   +3 more
doaj   +1 more source

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