PLoS ONE, 2015 MIS416 is an intact minimal cell wall skeleton derived from Proprionibacterium acnes that is phagocytosed by antigen presenting cells, including dendritic cells (DCs).
Francesco Mainini +4 more
doaj +1 more source
Albumin nanoparticles for glutathione-responsive release of cisplatin: new opportunities for medulloblastoma treatment [PDF]
, 2016 Redox-responsive nanoparticles were synthesized by desolvation of bovine serum albumin followed by disulfide-bond crosslinking with N, Nʹ-Bis (acryloyl) cystamine. Dynamic light scattering and transmission electron microscopy studies revealed spherical
Abballe, Luana +9 more
core +1 more source
The quiescin sulfhydryl oxidase (hQSOX1b) tunes the expression of resistin-like molecule alpha (RELM-α or mFIZZ1) in a wheat germ cell-free extract. [PDF]
PLoS ONE, 2013 Although disulfide bond formation in proteins is one of the most common types of post-translational modifications, the production of recombinant disulfide-rich proteins remains a challenge.
Wael Gad +9 more
doaj +1 more source
Hierarchical formation of disulphide bonds in the immunoglobulin Fc-Fragment is assisted by Protein Disulphide Isomerase [PDF]
, 2004 Antibodies provide an excellent system to study the folding and assembly of all β-sheet proteins and to elucidate the hierarchy of intra/inter chain disulfide bonds formation during the folding process of multimeric and multidomain proteins.
F. Vinci +6 more
core +1 more source
Disulfide Bond Formation in the Periplasm of Escherichia coli
EcoSal Plus, 2019 The formation of disulfide bonds is critical to the folding of many extracytoplasmic proteins in all domains of life. With the discovery in the early 1990s that disulfide bond formation is catalyzed by enzymes, the field of oxidative folding of proteins ...
Bruno Manta, D. Boyd, M. Berkmen
semanticscholar +1 more source
Self‐healing polyurethane based on disulfide bond and hydrogen bond
, 2018 Tough and transparent polyurethane networks with self-healing capability at mild temperature conditions were successfully prepared in a 1-pot procedure. The self-healing ability of synthesized polyurethane comes from the covalent disulfide metathesis and
Xiaoxia Jian +3 more
semanticscholar +1 more source
Molecules, 2020 The polypeptide backbone of proteins is held together by two main types of covalent bonds: the peptide bonds that link the amino acid residues and the disulfide bonds that link pairs of cysteine amino acids. Disulfide bonds form as a protein folds in the
Philip J. Hogg
doaj +1 more source
Radically Different Thioredoxin Domain Arrangement of ERp46, an Efficient Disulfide Bond Introducer of the Mammalian PDI Family [PDF]
, 2014 SummaryThe mammalian endoplasmic reticulum (ER) contains a diverse oxidative protein folding network in which ERp46, a member of the protein disulfide isomerase (PDI) family, serves as an efficient disulfide bond introducer together with Peroxiredoxin-4 (
Akiyama, Shuji +10 more
core +1 more source
Nano letters (Print), 2019 Single-domain VHH antibodies are promising reagents for medical therapy. A conserved disulfide bond within the VHH framework region is known to be critical for thermal stability, however, no prior studies have investigated its influence on the stability ...
Haipei Liu, V. Schittny, M. Nash
semanticscholar +1 more source
Model building of disulfide bonds in proteins with known three-dimensional structure [PDF]
, 1988 As an aid in the selection of sites in a protein where a disulfide bond might be engineered, a computer program has been developed. The algorithm starts with the generation of Cβ positions from the N, Cα and C atom coordinates available from a three ...
Dijkstra, Bauke W., Hazes, Bart
core +2 more sources