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A novel method for the mechanochemical synthesis of unsymmetrical disulfides using phosphorodithioic acid derivatives [PDF]
Scientific ReportsIn this study, we report the efficient synthesis of unsymmetrical disulfides using a mechanochemical ball-milling approach. This research successfully yielded alkyl-alkyl, alkyl-aryl, and aryl-aryl unsymmetrical disulfides without any detectable ...
Mikołaj Walter +4 more
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Photocatalytic Bilateral Disulfuration of Thioethers Toward α‐Sulfide Disulfides With Antibacterial Activity [PDF]
Advanced Scienceα−Sulfide disulfides represent valuable motifs in organic and pharmaceutical chemistry. However, the limited availability of synthetic approaches for α−sulfide disulfides has impeded progress in this field.
Qingqiang Tian +4 more
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Thiol Isomerases: Enzymatic Mechanisms, Models of Oxidation, and Antagonism by Galloylated Polyphenols [PDF]
AntioxidantsThiol isomerases are a family of enzymes that participate in oxidative protein folding. They contain highly reactive vicinal thiols in a CXXC motif within their catalytic domains to mediate thiol-disulfide switching as part of their reductase, oxidase ...
Osamede C. Owegie +3 more
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Synthesis of disulfides and 3-sulfenylchromones from sodium sulfinates catalyzed by TBAI [PDF]
Beilstein Journal of Organic ChemistryA new synthetic method for disulfides and 3-sulfenylchromones is reported. This innovative approach is based on the tetrabutylammonium iodide (TBAI)/H2SO4 reduction system using sodium sulfinate as key component, thus eliminating the need for thiols and ...
Zhenlei Zhang +6 more
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Synthesis and Biological Activity of Unsymmetrical Monoterpenylhetaryl Disulfides
Molecules, 2022 New unsymmetrical monoterpenylhetaryl disulfides based on heterocyclic disulfides and monoterpene thiols were synthesized for the first time in 48–88% yields.
Denis V. Sudarikov +12 more
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Identification of allosteric disulfides from labile bonds in X-ray structures [PDF]
Royal Society Open Science, 2018 Protein disulfide bonds link pairs of cysteine sulfur atoms and are either structural or functional motifs. The allosteric disulfides control the function of the protein in which they reside when cleaved or formed.
Aster E. Pijning +4 more
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The effect of tensile stress on the conformational free energy landscape of disulfide bonds. [PDF]
PLoS ONE, 2014 Disulfide bridges are no longer considered to merely stabilize protein structure, but are increasingly recognized to play a functional role in many regulatory biomolecular processes.
Padmesh Anjukandi +3 more
doaj +1 more source
Advanced Energy & Sustainability Research, 2023 Selective coupling of thiols to produce disulfides is one very important and classic type of coupling reactions. Herein, an environmentally friendly and practical photocatalytic system for oxidative coupling of thiols to disulfides is developed.
Fengyun Su +8 more
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Scientific Reports, 2022 In this research, a simple, efficient and novel protocol is eveloped for the direct synthesis of symmetrical disulfides using dipotassium 1,3,4-thiadiazole-2,5-bis(thiolate) as a new, low toxicity, inexpensive, stable solid and free of foul-smelling ...
Mohammad Soleiman-Beigi +3 more
doaj +1 more source
Protein Engineering Design and Selection, 2003 The formation of a disulfide bond between adjacent cysteine residues is accompanied by the formation of a tight turn of the protein backbone. In nearly 90% of the structures analyzed a type VIII turn was found. The peptide bond between the two cysteines is in a distorted trans conformation, the omega torsion angle ranges from 159 to -133 degrees, with ...
Carugo, O. +6 more
openaire +4 more sources