Results 41 to 50 of about 26,459 (307)
Optimized methods for preparation of 6I-(ω-sulfanyl-alkylene-sulfanyl)-β-cyclodextrin derivatives
Beilstein Journal of Organic Chemistry, 2016 A general high-yielding method for the preparation of monosubstituted β-cyclodextrin derivatives which have attached a thiol group in position 6 is described.
Eva Bednářová +2 more
doaj +1 more source
Preparation of Unsymmetrical Disulfides from Thioacetates and Thiosulfonates [PDF]
, 2019 A method for the transformation of organic thioacetates, a widely used functionality for the preparation of self-assembled monolayers on gold surfaces, into unsymmetrical disulfides is reported.
Zwick, Patrick +8 more
core +1 more source
Efficient Synthesis of Pyrrole Disulfides Catalyzed by Lipase in Ethanol
, 2023 Disulfides, as fundamental scaffolds, are widely present in peptides, natural products, and pharmaceutical molecules. However, traditional synthesis of disulfides often involves the utilization of toxic reagents or environmentally unfriendly reaction ...
Zhi Wang +6 more
core +1 more source
Frontiers in Immunology, 2019 Platelets play an essential role in maintaining homeostasis in the circulatory system after an injury by forming a platelet thrombus, but they also occupy a central node in the intravascular innate immune system.
Oskar Eriksson +4 more
doaj +1 more source
Thiol Metabolism and Volatile Metabolome of Clostridioides difficile
Frontiers in Microbiology, 2022 Clostridioides difficile (previously Clostridium difficile) causes life-threatening gut infections. The central metabolism of the bacterium is strongly influencing toxin production and consequently the infection progress. In this context, the composition
Peter Biwer +6 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Molecules, 2018 A new protocol for the preparation of thioaryl-porphyrins is described. The compounds were prepared from different disulfides employing NaBH4 as a reducing agent.
Patrícia Foletto +8 more
doaj +1 more source
Cross-strand disulfides in the non-hydrogen bonding site of antiparallel β-sheet (aCSDns): poised for biological switching† [PDF]
RSC Advances, 2015 Forbidden disulfides are stressed disulfides found in recognisable protein contexts previously defined as structurally forbidden. The torsional strain of forbidden disulfides is typically higher than for structural disulfides, but not so high as to ...
Naomi L. Haworth, Merridee A. Wouters
doaj +1 more source
Quantification of thiols and disulfides [PDF]
Biochimica et Biophysica Acta (BBA) - General Subjects, 2014 Disulfide bond formation is a key posttranslational modification, with implications for structure, function and stability of numerous proteins. While disulfide bond formation is a necessary and essential process for many proteins, it is deleterious and disruptive for others.
Winther, Jakob R., Thorpe, Colin
openaire +3 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source