Results 51 to 60 of about 40,867 (306)

Controlled Cellular Delivery of Amphiphilic Cargo by Redox‐Responsive Nanocontainers

Advanced Science, 2019
The specific transport of amphiphilic compounds such as fluorescently labeled phospholipids into cells is a prerequisite for the analysis of highly dynamic cellular processes involving these molecules, e.g., the intracellular distribution and metabolism ...
Wilke C. deVries, Sergej Kudruk, David Grill, Maximilian Niehues, Anna Livia Linard Matos, Maren Wissing, Armido Studer, Volker Gerke, Bart Jan Ravoo   +8 more
doaj   +1 more source

Study of Cytotoxicity and Internalization of Redox-Responsive Iron Oxide Nanoparticles on PC-3 and 4T1 Cancer Cell Lines

Pharmaceutics, 2022
Redox-responsive and magnetic nanomaterials are widely used in tumor treatment separately, and while the application of their combined functionalities is perspective, exactly how such synergistic effects can be implemented is still unclear.
Timur R. Nizamov, Artem R. Iliasov, Stepan S. Vodopyanov, Irina V. Kozhina, Igor G. Bordyuzhin, Dmitry G. Zhukov, Anna V. Ivanova, Elizaveta S. Permyakova, Pavel S. Mogilnikov, Daniil A. Vishnevskiy, Igor V. Shchetinin, Maxim A. Abakumov, Alexander G. Savchenko   +12 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Oxidative protein biogenesis and redox regulation in the mitochondrial intermembrane space [PDF]

, 2016
Mitochondria are organelles that play a central role in cellular metabolism, as they are responsible for processes such as iron/sulfur cluster biogenesis, respiration and apoptosis.
MacPherson, Lisa, Manganas, Phanee, Tokatlidis, Kostas   +2 more
core   +1 more source

Vicinal disulfide turns [PDF]

Protein Engineering Design and Selection, 2003
The formation of a disulfide bond between adjacent cysteine residues is accompanied by the formation of a tight turn of the protein backbone. In nearly 90% of the structures analyzed a type VIII turn was found. The peptide bond between the two cysteines is in a distorted trans conformation, the omega torsion angle ranges from 159 to -133 degrees, with ...
Carugo, O., Cemazar, M., Zahariev, S., Hudaky, I., Gaspari, Z., Perczel, A., Pongor, S.   +6 more
openaire   +5 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Novel strategies for the synthesis of unsymmetrical glycosyl disulfides [PDF]

, 2016
yesNovel strategies for the efficient synthesis of unsymmetrical glycosyl disulfides are reported. Glycosyl disulfides are increasingly important as glycomimetics and molecular probes in glycobiology. Sialosyl disulfides are synthesised directly from the
Adinolfi, Al-Saraireh, Andre, Aversa, Bailey, Bernardes, Bradley R. Springett, Brito, Caraballo, Caraballo, Davis, Falconer, Fernandez-Gonzalez, Ferrier, Gamblin, Goreti Ribeiro Morais, Grayson, Grayson, Hamachi, Harp, Hummel, Illyes, Kiefel, Knapp, Liang, Liang, Lisa Schröder, Macindoe, Mandal, Martin Pauze, Matthew Northrop, Murthy, Musiejuk, Pei, Pei, Ribeiro Morais, Ribeiro Morais, Ribeiro Morais, Robert A. Falconer, Stellenboom, Szilagyi   +40 more
core   +1 more source

Advancing Electronic Application of Coordination Solids: Enhancing Electron Transport and Device Integration via Surface‐Mounted MOFs (SURMOFs)

Advanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of coordination solids, enabled by the surface‐mounted metal‐organic framework (SURMOF) platform, is on the cusp of generating the organic counterpart of the epitaxy of inorganics. The programmable and sequential SURMOF protocol, optimized by machine learning (ML), is suited for accessing high‐quality thin films of ...
Zhengtao Xu, Christof Wöll, Stefan Bräse   +2 more
wiley   +1 more source

3D‐Printed Sulfur‐Derived Polymers With Controlled Architectures for Lithium‐Sulfur Batteries

Advanced Functional Materials, EarlyView.
Rheology‐guided formulation design for direct ink writing enables the fabrication of 3D sulfur copolymer cathodes with controlled architectures for lithium‐sulfur batteries. The printed electrodes exhibit multiscale porosity and high sulfur utilization, delivering enhanced electrochemical performance compared to conventional cast electrodes.
Bin Ling, Haoran Wang, Pan Yang, Rishav Agrawal, Alex R. Neale, Laurence J. Hardwick, Tom Hasell, Esther García‐Tuñón   +7 more
wiley   +1 more source

H5PV2Mo10O40 as an efficient catalyst for the oxidation of thiols to the corresponding disulfides using hydrogen peroxide as the oxidant [PDF]

Journal of the Serbian Chemical Society, 2011
The H5PV2Mo10O40 catalyzed the oxidation of thiols to their homodisulfides using hydrogen peroxide as the oxidant under mild conditions is reported.
MAJID HERAVI, ABDOLLAH FALLAH SHOJAEI, OHAMAD ALI REZVANI   +2 more
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