Results 71 to 80 of about 16,675 (216)

Medicaid Managed Care Plan Alignment With State Substance Use Disorder Treatment Coverage Requirements

The Milbank Quarterly, EarlyView.
Policy Points States contract with Medicaid managed care plans to administer benefits for roughly 70 million Medicaid enrollees, yet little is known about how plan benefit policies for substance use disorder (SUD) treatment medications align with state requirements.
SAGE R. FELTUS, CHRISTINA M. ANDREWS, LAUREN PETERSON, COLLEEN M. GROGAN, AMANDA J. ABRAHAM, OLIVIA M. HINDS, MAUREEN T. STEWART   +6 more
wiley   +1 more source

Disulfiram Encephalopathy Presenting with Delirium, Epilepsy, and a Manic Episode: A Case Report

Addicta: The Turkish Journal on Addictions
Disulfiram is an agent used in the treatment of alcohol use disorder and causes a disulfiram-ethanol reaction, which can result in serious adverse effects when taken with alcohol. Although rare, disulfiram can cause neuropsychiatric side effects even in
Zehra Uçar Hasanlı, Mustafa Danışman, Gamze Zengin İspir, Kübra Sezer Katar   +3 more
doaj   +1 more source

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Efficacy and safety of transcranial direct current stimulation in alcohol use disorder: A randomized controlled triple‐blind trial

Addiction, EarlyView.
Abstract Background and aims Current treatment options for alcohol use disorder are limited. Transcranial direct current stimulation has been proposed as a therapeutic approach, but evidence remains scarce. This study aimed to compare active vs. sham transcranial direct current stimulation to evaluate its efficacy and safety in reducing alcohol ...
Benoit Trojak, Anne Sauvaget, Wissam El Hage, Thomas Wallenhorst, Benjamin Rolland, Philippe Nubukpo, Ghina Harika‐Germaneau, David Szekely, Julie Giustiniani, Marc Auriacombe, Georges Brousse, Sébastien Guillaume, Maxime Bubrovszky, Benjamin Petit, Clémence Cabelguen, Hussein El Ayoubi, Suzanne Rankin, Agnès Soudry‐Faure, Karine Goueslard, Anastasia Demina   +19 more
wiley   +1 more source

Predictive validity of Alcohol Use Disorder Identification Test – Consumption (AUDIT‐C) for register‐based alcohol‐attributable events among general‐population men and women of different ages

Addiction, EarlyView.
Abstract Background and aims Originally developed for clinical screening for hazardous alcohol use, the Alcohol Use Disorder Identification Test – Consumption (AUDIT‐C) is also widely used in epidemiological research and monitoring. However, its cutoff values may not suit all purposes, and evidence on its predictive validity is limited. We examined how
Pia Mäkelä, Jaakko Reinikainen, Sarah Callinan, Marke Jääskeläinen, Kaisa Kuurne, Tomi Lintonen, Solja Niemelä, Jonna Levola   +7 more
wiley   +1 more source

Cyclic Treatment With WIN 18,446, a Potential Male Contraceptive, is as Effective as Continuous Treatment for Suppression of Spermatogenesis in Mice

Andrology, EarlyView.
ABSTRACT Background Retinoic acid plays a critical role in spermatogenesis during both spermatogonial differentiation and spermiation. Mice lacking enzymes that synthesize retinoic acid, Aldh1a1/1a2, in the testes are infertile. WIN 18,446 reversibly inhibits spermatogenesis by inhibiting ALDH1A1/1A2 and is a promising approach to male contraception ...
Jisun Paik, Jessica M. Snyder, Haley A. Martin, John K. Amory   +3 more
wiley   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Hypoxia‐preconditioned adipose‐derived mesenchymal stem cells‐derived exosomes transferring H19 obstruct neutrophil extracellular traps formation via HOXA5‐mediated inactivation of TLR4/NF‐κB/NLRP3 inflammatory signaling

Journal of Diabetes Investigation, EarlyView.
In this study, we uncovered that Hypo‐Exo transferring H19 promoted diabetic wound healing by repressing NETs formation via the miR‐130a/b‐3p/HOXA5 pathway to inactivate the TLR4/NF‐κB/NLRP3 inflammatory signaling. ABSTRACT Background Hypoxia‐stimulated adipose‐derived mesenchymal stem cells (ADSCs)‐derived exosomes (Hypo‐Exo) have a positive impact on
Li Qian, Xianxi Meng, Bairong Fang, Li Pi   +3 more
wiley   +1 more source

Disulfiram Induced Psychosis: A Case Report

Neurologijos seminarai
Introduction. Disulfiram is one of three medications approved by the Federal Drug Administration (FDA) to treat alcohol dependence. Patients tend to abstain from alcohol to avoid the unpleasant effects of alcohol toxicity. There may be some side effects,
D. R. Survilaitė, R. Žemaitytė
doaj   +3 more sources

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source