Results 41 to 50 of about 1,788 (179)
PEG400 regulates Falcipain 2 activity through an allosteric mechanism
The FEBS Journal, EarlyView.Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath +2 more
wiley +1 more source
Biogenesis of TNF‐α‐insights into proteostasis and inflammation
The FEBS Journal, EarlyView.TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar +3 more
wiley +1 more source
Kell‐Score—A web resource for estimating the immunogenicity of novel Kell blood group variants
British Journal of Haematology, EarlyView.
Gabriele Mayr +4 more
wiley +1 more source
The FEBS Journal, EarlyView.Basement membrane (BM) homeostasis relies on a balance between integrity, controlled remodelling and pathological degradation. Increased protease expression beneath the BM, along with reduced levels of endogenous protease inhibitors, drives the transition from a continuous, protective barrier to a discontinuous interface.
Clara Legendre +2 more
wiley +1 more source
Effects of repeated exposure to ozonated water on hair fibre structure and integrity: Part I
International Journal of Cosmetic Science, EarlyView.Repeated exposure to ozonated water caused cumulative oxidative changes in hair, altering structural integrity, thermal behaviour and mechanical properties. The findings reveal a distinct ozone‐induced damage profile that progresses beyond the cuticle, challenging claims of hair‐revitalizing benefits. Abstract Objective Ozone has recently been marketed
Pedro Augusto Laurindo Igreja Marrafa +5 more
wiley +1 more source
Targeted keratin repair: A plant‐based approach to hair strength and surface restoration
International Journal of Cosmetic Science, EarlyView.Application of Avena strigosa seed extract may reinforce keratin bonding, restoring hair fibre integrity by promoting intramolecular interactions at damaged sites of keratin proteins. Abstract Objective Chemical and thermal stress disrupts the intramolecular and intermolecular interactions that stabilize hair keratin, leading to structural degradation ...
Emina Besic Gyenge +6 more
wiley +1 more source
Insect Molecular Biology, EarlyView.Genome‐wide systematic annotation identified 81 odorant receptors (ORs) and 49 odorant‐binding proteins (OBPs) in the tobacco budworm, Chloridea virescens. Phylogenetic analyses revealed chemosensory gene diversification in Heliothinae and extensive lineage‐specific duplications in C.
Rong Guo, Boyang Ni, Megan L. Fritz
wiley +1 more source
Insect Molecular Biology, EarlyView.Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto +2 more
wiley +1 more source
The mechanism of disulphide reduction by mitochondria [PDF]
Biochemical Journal, 1968 1. Cystamine was reduced to the corresponding thiol by rat liver mitochondria, even in the presence of rotenone or antimycin A. 2. The reduction of disulphides was stimulated by the accumulation of NADH or by the addition of NADH to osmotically ‘shocked’ mitochondria. 3.
openaire +2 more sources