Results 61 to 70 of about 1,788 (179)

Unravelling the Significance of Cystatin C and Bunina Bodies in Amyotrophic Lateral Sclerosis Pathogenesis

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
ABSTRACT Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a fatal neurodegenerative disease primarily affecting motor neurons. Two key protein inclusions found in lower motor neurons serve as neuropathological hallmarks of the disease in human tissue: the TDP43‐positive inclusion and the cystatin C‐positive Bunina body.
Sarah M. Granger   +5 more
wiley   +1 more source

Mex‐3 RNA‐binding family member A limits macrophage ferroptosis‐associated injury linked to the SLC7A11/GPX4 pathway in diabetic atherosclerosis

open access: yesClinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Diabetes reduces macrophage MEX3A and aggravates atherosclerotic plaque instability. MEX3A stabilises Slc7a11 and Gpx4 mRNAs to sustain SLC7A11/GPX4 antioxidant defence. MEX3A deficiency promotes macrophage ferroptosis, lipid peroxidation and mitochondrial injury. Ferrostatin‐1 partially attenuates ferroptotic injury and diabetic plaque destabilisation.
Yanpeng Ma   +7 more
wiley   +1 more source

LECHER'S DISULPHIDE FROM TETRAMETHYLTHIOCARBAMIDE. CONSTITUTION OF 'FORMAMIDINE DISULPHIDE'

open access: yes, 1951
The supposed disulphide oxidation product of tetramethyithiocarbamide has been shown to be derived cram a single molecule of the latter. Its properties indicate structural analogy with "formam­idine disulphide", the oxidation product of NH2. CS. NH2.
openaire   +2 more sources

DSDBASE 2.0: updated version of DiSulphide dataBASE, a database on disulphide bonds in proteins. [PDF]

open access: yesDatabase (Oxford), 2022
Kalmankar NV   +4 more
europepmc   +1 more source

Integrative Assessment of Desmostachya bipinnata (L.) Root Extract: Anti‐Inflammatory and Antinociceptive Effects Supported by Molecular Docking and Network Pharmacology

open access: yesFlavour and Fragrance Journal, Volume 41, Issue 4, Page 841-858, July 2026.
The ethanolic root extract of Desmostachya bipinnata exhibited significant anti‐inflammatory and antinociceptive activities in in vitro, in vivo and in silico models, revealing bioactive compounds capable of modulating key inflammatory targets and supporting the plant's traditional therapeutic potential.
Muhammad Hussnain Siddique   +6 more
wiley   +1 more source

Disulphide bonds of ovalbumins [PDF]

open access: yesBiochemical Journal, 1968
L A, Fothergill, J E, Fothergill
openaire   +2 more sources

Comparative Effects of Laparotomy and Laparoscopy‐Assisted Embryo Transfer on Oxidative Stress and Thiol–Disulphide Homeostasis in Tuj Ewes

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Laparoscopic embryo transfer in Tuj ewes induces less oxidative stress and better preserves thiol–disulphide homeostasis than laparotomy. These findings indicate that minimally invasive approaches better maintain redox balance and antioxidant defence during embryo transfer procedures.
Murat Can Demir   +7 more
wiley   +1 more source

Evidence for a Two‐Step Model for Activation of GPR25 by the Chemoattractant CXCL17

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT CXCL17 was recently reported to activate GPR25, a receptor expressed by T‐regulatory cells. Although classified as a chemokine, the activity of CXCL17 is ablated by minor C‐terminal truncation, suggesting a novel mode of receptor activation. We set out to test this hypothesis by mutagenesis. GPR25 was expressed in the murine pre‐B cell line L1.
Wuqing Yang   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy