Results 41 to 50 of about 485 (159)

Differential medication overuse risk of novel anti-migraine therapeutics [PDF]

, 2020
Medication overuse headache is estimated to affect 2% of the population, and is ranked in the top 20 most disabling disorders due to its high level of disability. Several therapies used in the treatment of acute migraine are thought to be associated with
Strother, Lauren C; id_orcid, Goadsby, Peter J; id_orcid, Holland, Philip R; id_orcid, Saengjaroentham, Chonlawan, Dripps, Isaac, Sultan Jabir, Mohammad Rayhan, Pradhan, Amynah   +6 more
core   +1 more source

Real‐world diagnosis and treatment of individuals with migraine in the United States: The Migraine Insights in Diagnosis and Treatment (MIND) study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The objective of this study was to describe the real‐world diagnosis and treatment patterns of individuals newly diagnosed with migraine in the United States (US). Background Over 10% of adults in the US are living with migraine.
Fred Cohen, Vincent Martin, Avani Patel, Shelby L. Corman, Katie B. Tellor, Meghan Fajardo, D. Cortney Hayflinger, Simon Dagenais   +7 more
wiley   +1 more source

Nueva era terapéutica para el ataque de migraña con los recientemente aprobados anticuerpos monoclonales, ditanes y gepantes [PDF]

Revista de Neurología
Treatment of migraine attacks is advised in all patients, using non-steroidal anti-inflammatory drugs when the pain is mild and triptans when the pain intensity is moderate-severe. However, the effectiveness of these drugs is moderate, a high percentage of patients have side effects, and triptans are contraindicated in people with a history of stroke ...
Mínguez-Olaondo, A, López-Bravo, A, Quintas, S, Nieves-Castellanos, C, Layos-Romero, A, Belvís, R, Irimia, P, Díaz-Insa, S   +7 more
openaire   +3 more sources

Recombinant Human Thrombopoietin Reduces the Need for Platelet Transfusion in Patients With Chronic Liver Disease and Thrombocytopenia

American Journal of Hematology, Volume 101, Issue 10, Page 2571-2580, October 2026.
ABSTRACT Chronic liver disease (CLD)‐related thrombocytopenia can limit the feasibility of invasive procedures. Recombinant human thrombopoietin (rhTPO) has demonstrated a favorable safety profile without hepatotoxicity. We evaluated the efficacy and safety of rhTPO in patients with CLD‐related thrombocytopenia who were undergoing elective invasive ...
Yifan Han, Ning Lin, Jinghang Xu, Sikui Wang, Jinglan Jin, Jia Shang, Yongning Xin, Youwen Tan, Dazhi Zhang, Jinlin Hou, Ping An, Wen Xie, Yujuan Guan, Qingfang Xiong, Hong Wu, Huiguo Ding, Yu Chen, Rongkuan Li, Zhili Wen, Mingqin Lu, Jinhui Yang, Zhongyin Zhou, Yongjian Zhou, Zujiang Yu, Kecan Lin, Wei Wang, Yan Huang, Yuemin Nan, Xinhua Luo, Rongshu Shi, Yi Kang, Tao Han, Shiyan Chen, Kai Wang, Yunfeng Shan, Jiaping Li, Pingguo Liu, Zheng Lu, Jun Chen, Zhen Liu, Liaoyun Zhang, Li Yang, Jifang Sheng, Zhan Zeng, Yanyan Yu, Xiaoyuan Xu   +45 more
wiley   +1 more source

A 7‐mm Covered TIPS Reduces Hepatic Encephalopathy Without Increasing Rebleeding in Cirrhotic Patients With Small Liver: A Randomized Study

Liver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background/Aims International guidelines recommend initiating transjugular intrahepatic portosystemic shunt (TIPS) placement with an 8‐mm stent. However, there is an evident lack of randomized controlled trials evaluating TIPS diameters < 8 mm in cirrhotic patients with a relatively small liver. The aim of this study was to determine whether 7 
Fuquan Liu, Kan Zhang, Yu Zhang, Quanwei He, Mingming Meng, Xuemei Ma, Bing Zhu, Yifan Wu, Linjing An, Yifan Lv, Fuhuang Lin, Ke Zhang, Bowen Liu, Xiujuan Chang, Huiguo Ding, Jiangtao Liu, Yan Chen, Yongping Yang   +17 more
wiley   +1 more source

Sodium Intake and Osteoporosis Risk: Evidence From NHANES and Mendelian Randomization Analysis

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
This study combined cross‐sectional data from the National Health and Nutrition Examination Survey (NHANES) with Mendelian Randomization (MR) analysis to systematically investigate the relationship between sodium intake and osteoporosis. The results showed that within a specific intake range (> 6150 mg/day), sodium intake was significantly negatively ...
Yunxiao Ji, Zibo Fan, Rugang Zhao, Changsong Zhao, Qiang Zhang, Xinbao Wu   +5 more
wiley   +1 more source

Migraine: Beyond the headache. A brief review of pathophysiology and targeted pharmaco-therapeutics

, 2023
Headaches are common. The International Headache Society’s (IHS) International Classification of Headache Disorders, 3rd edition (ICHD 3), lists numerous primary headache disorders that primary care providers and even neurologists could find ...
Patt -Bogut, Maureen A
core   +1 more source

Admission‐Time Clinicolaboratory Phenotypes for Early Differentiation of Severe Fever With Thrombocytopenia Syndrome and Hemorrhagic Fever With Renal Syndrome

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Early differentiation of severe fever with thrombocytopenia syndrome (SFTS) and hemorrhagic fever with renal syndrome (HFRS) remains difficult in endemic settings. In this single‐center retrospective comparative study, we analyzed admission‐time demographic, clinical, and laboratory data from 330 hospitalized patients with laboratory‐confirmed
Ruize Ma, Yanli Xu, Shuwen Ding, Ruihua Zhang, Jingxia Wang, Zhouling Jiang, Ling Lin, Zhihai Chen   +7 more
wiley   +1 more source

Transcriptional Profiling of Growth Hormone–Secreting Pituitary Adenoma Stem‐Like Cells: Unveiling the Significant Role of CXCR4 in Tumorigenesis and Clinical Applications

MedComm, Volume 7, Issue 9, September 2026.
Growth hormone–secreting pituitary adenomas harbor hPASCs (human pituitary adenoma stem‐like cells). Genetic profiling of hPASCs identified CXCR4 as a significant gene orchestrating a regulatory network in the self‐renewal and differentiation of hPASCs, as well as the modulation of tumor cells and the microenvironment.
LinHao Yuan, Hao Yang, BaoWang Li, Huimin Sui, Peiliang Li, Xu Wang, Jiang Li, Guijun Jia, Zhaohui Zhu, Deling Li, Wang Jia, Peng Kang   +11 more
wiley   +1 more source

Natural Killer Cell Dysfunction Is Emerging During Midlife Obesity

Aging Cell, Volume 25, Issue 9, September 2026.
Midlife obesity was associated with impaired NK cell function, including decreased degranulation and IFN‐γ production. The loss of NK cell function might explain the greater mortality risk in middle‐aged individuals, highlighting the importance of monitoring immune alterations during midlife.
Ruojia Biao, Xudong Wang, Jiantao Fu, Yifan Guo, Junming He, Juan Du   +5 more
wiley   +1 more source