Results 11 to 20 of about 45,446 (245)

Stemarane Diterpenes and Diterpenoids

International Journal of Molecular Sciences, 2019
In this article the scientific activity carried out on stemarane diterpenes and diterpenoids, isolated over the world from various natural sources, was reviewed. The structure elucidation of stemarane diterpenes and diterpenoids was reported, in addition to their biogenesis and biosynthesis.
Leonelli, Francesca, Valletta, Alessio, Migneco, Luisa Maria, Marini Bettolo, Rinaldo   +3 more
openaire   +2 more sources

The Diterpenes Ovoideal A–G from Tirpitzia ovoidea

Molecules, 2014
Seven new diterpenes, named ovoideal A (1), B (2), C (3), D (4), E (5), F (6) and G (7), have been isolated along with eleven known diterpenes 8–18 from the petroleum ether soluble fraction of an ethanol extract of the aerial parts of Tirpitzia ovoidea ...
Dan Su, Xue-Yan Yang, Xu Feng, Ming-Ying Shang, Shao-Qing Cai   +4 more
doaj   +1 more source

Contribution of microscopy for understanding the mechanism of action against trypanosomatids [PDF]

, 2018
Transmission electron microscopy (TEM) has proved to be a useful tool to study the ultrastructural alterations and the target organelles of new antitrypanosomatid drugs.
A Martinez-Palomo, A Montalvetti, A Rassi, AB Penissi, AE Eakin, AH Kolien, AJ Solari, AM Sánchez, Ana Yecê das Neves Pinto, C Brack, CF Silva Da, D Gonzalez-Pacanowska, DA Campbell, DA Johnston, DJ Hammond, DV Andrade, E Bontempi, E Lozano, E Lozano, E Lozano, EO Ogbadoiyi, ES Garcia, ES Lozano, F Dos Reis, FR Opperdoes, FR Opperdoes, FR Opperdoes, FS Laranja, H Meyer, H Meyer, J Aldunate, J Lukes, J McKerrow, J Mottram, JA Urbina, JA Urbina, JA Urbina, JA Urbina, JC Engel, JC Linder, JCP Dias, JCP Dias, JD Bergstrom, JD Maya, JF Turrens, JJ Marr, JL Avila, JL Avila, Juliano de Toledo, K Lazardi, K Miranda, K Miranda, KH Lee, L Simpson, LV Muschietti, M Meirelles, M Nieto, MC Elias, MCQB Elias, MR Ariyanayagam, MR Ariyanayagam, NM Sayed El, O Campetella, OS Giordano, OS Giordano, P Barrera, P Webster, PF Pimenta, R Docampo, S Sepúlveda-Boza, SD Brengio, SR Wilkinson, T Souto-Padron, T Souto-Padron, T Souto-Padron, T Souto-Padron, TA Shapiro, TS Tiuman, V Jimenez-Ortiz, V Sülsen, VP Sülsen, VP Sülsen, VV Costantino, W Souza De, W Souza De, W Souza De, W Souza De, W Souza De, W Souza De, Wanderley de Souza, WE Gutteridge   +90 more
core   +1 more source

Understanding the role of active site residues in CotB2 catalysis using a cluster model

Beilstein Journal of Organic Chemistry, 2020
Terpene cyclases are responsible for the initial cyclization cascade in the multistep synthesis of a large number of terpenes. CotB2 is a diterpene cyclase from Streptomyces melanosporofaciens, which catalyzes the formation of cycloocta-9-en-7-ol, a ...
Keren Raz, Ronja Driller, Thomas Brück, Bernhard Loll, Dan T. Major   +4 more
doaj   +1 more source

A Review of Diterpenes from Marine-Derived Fungi: 2009–2021

Molecules, 2022
Marine-derived fungi are important sources of novel compounds and pharmacologically active metabolites. As an important class of natural products, diterpenes show various biological activities, such as antiviral, antibacterial, anti-inflammatory ...
Peng Qiu, Jinmei Xia, Haitao Zhang, Donghai Lin, Zongze Shao   +4 more
doaj   +1 more source

Chemical and antimicrobial analyses of Sideritis romana L. subsp. purpurea (Tal. ex Benth.) Heywood, an endemic of the Western Balkan [PDF]

, 2017
A comprehensive study on essential oil and different solvent extracts of Sideritis romana L. subsp. purpurea (Tal. ex Benth.) Heywood (Lamiaceae) from Montenegro is reported. The gas chromatography-mass spectrometry analysis of the essential oil revealed
Božović, Mijat, Cipolla, Alessia, De Angelis, Massimiliano, Garzoli, Stefania, Oliva, Alessandra, Ragno, Rino, Tadić, Vanja, Vullo, Vincenzo   +7 more
core   +1 more source

Pseudopterosin Biosynthesis: Aromatization of the Diterpene Cyclase Product, Elisabethatriene

Marine Drugs, 2003
: Putative precursors in pseudopterosin biosynthesis, the hydrocarbons isoelisabethatriene (10) and erogorgiaene (11), have been identified from an extract of Pseudopterogorgia elisabethae collected in the Florida Keys.
Amber C. Kohl, Russell G. Kerr
doaj   +1 more source

Functional characterization of the cytochrome P450 monooxygenase CYP71AU87 indicates a role in marrubiin biosynthesis in the medicinal plant Marrubium vulgare. [PDF]

, 2019
BackgroundHorehound (Marrubium vulgare) is a medicinal plant whose signature bioactive compounds, marrubiin and related furanoid diterpenoid lactones, have potential applications for the treatment of cardiovascular diseases and type II diabetes.
Addison, J Bennett, Dhanota, Puja, Fiehn, Oliver, Karunanithi, Prema S, Tong, Shen, Zerbe, Philipp   +5 more
core   +6 more sources

<em>An ent</em>-Kaurane-Type Diterpene in <em>Croton antisyphiliticus</em> Mart.

Molecules, 2012
<em>Croton antisyphiliticus </em>is a medicinal plant widely used in the treatment of microbial infections, especially those affecting the genital tract.
Ana Maria Pereira, Suzelei França, Bianca Bertoni, Paulo Pereira, Juliana Coppede, Silvia Taleb-Contini, Sarazete Pereira   +6 more
doaj   +1 more source

New Labdanes with Antimicrobial and Acaricidal Activity: Terpenes of Callitris and Widdringtonia (Cupressaceae)

Antibiotics, 2020
In spite of the evidence for antimicrobial and acaricidal effects in ethnobotanical reports of Callitris and Widdringtonia, the diterpene acids from Widdringtonia have never been described and no comparison to the Australian clade sister genus Callitris ...
Nicholas J. Sadgrove, Haytham Senbill, Ben-Erik Van Wyk, Ben W. Greatrex   +3 more
doaj   +1 more source