Results 61 to 70 of about 942 (157)

Kaurane-type diterpenes from Adenostemma lavenia O. Kuntze.

open access: yesChemical and Pharmaceutical Bulletin, 1990
Ten 11-oxygenated kauran-19-oic acids, ent-11α, 15α-dihydroxykaur-16-en-19-oic acid, ent-11α-hydroxy-15α-acetoxykaur-16-en-19-oic acid, ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic acid and adenostemmoic acids A-G and their nine glycosides, paniculosides II and III and adenostemmosides A-G were characterized from Adenostemma lavenia O. KUNTZE.
SHIMIZU, Shigeru   +3 more
openaire   +2 more sources

Study of Anti-Tuberculosis Activity Behaviour of Natural Kaurane and Trachylobane Diterpenes Compared with Structural Properties Obtained by Theoretical Calculations

open access: yesNatural Product Communications, 2017
A set of seven diterpenes, three kauranes and four trachylobanes, isolated from the African plant Psiadia punctulata were assayed against Mycobacterium tuberculosis and reached activity comparable with cycloserine, a second line drug used to treat ...
Ana C. F. Soares   +8 more
doaj   +1 more source

A New Kaurane Diterpene from the Leaves of Callicarpa macrophylla Vahl

open access: yesBiomedical & Pharmacology Journal, 2012
T he c hloroform extract of leaves of Callicarpa macrophylla Vahl. , yielded a new compound 16α - hydroxy - 17 - isopropylidino - 3 - oxo - phyllocladane along with calliterpenone and its monoacetate.
Vinay Kumar Verma   +2 more
openaire   +1 more source

PTP1B inhibitory activity of kaurane diterpenes isolated fromSiegesbeckia glabrescens

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2006
Protein tyrosine phosphatase 1B (PTP1B) is considered as a therapeutic target for the treatment of diabetes and obesity. In our preliminary screening study, a MeOH extract of the aerial part of Siegesbeckia glabrescens was found to inhibit PTP1B activity at 30 microg/mL.
Sohee, Kim   +7 more
openaire   +2 more sources

Cafestol and kahweol: coffee diterpenes with trypanocidal activity and cardioprotective effects

open access: yesFrontiers in Cellular and Infection Microbiology
IntroductionChagas disease (CD), caused by Trypanosoma cruzi, remains a major public health challenge in Latin America, affecting more than 7 million people worldwide and approximately 100 million individuals at risk of infection.
Juliana Magalhães Chaves Barbosa   +8 more
doaj   +1 more source

Kaurane diterpenes from the fruits of Zanthoxylum leprieurii (Rutaceae)

open access: yes, 2017
Abstract: The fruits of Zanthoxylum leprieurii Guill. & Perr. (Rutaceae) are traditionally used in Africa, particularly in Cameroon, as a spice and in the treatment of sickle cell anaemia. Phytochemical investigation on the fruits of this plant afforded five kaurane diterpenes, i.e., kaurenoic acid (1), xylopic acid (2), ent-kauran-16β-ol (3), ent-16β ...
Guetchueng, ST   +6 more
openaire  

Isolation and HPLC quantitation of kaurane-type diterpenes and cinnamic acid derivatives of long-term stored leaves of Mikania laevigata and Mikania glomerata

open access: yesAnais da Academia Brasileira de Ciências, 2013
The leaves of Mikania laevigata and Mikania glomerata are used in Brazil to treat respiratory affections, being kaurane-type diterpenes and coumarin considered as the bioactive compounds.
SUZAN K.V. BERTOLUCCI   +4 more
doaj  

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