Results 21 to 30 of about 21,898 (241)
Precision Matters: Minor Concentration Deviations of DMSO May Cause Major Efficacy Shifts
Angewandte Chemie, EarlyView.Low‐concentration dimethyl sulfoxide (DMSO) has long been regarded as biologically safe in drug discovery. However, increasing DMSO from 0.1% to 0.9% reduces photosensitizer PNA‐9 particle size from 657 nm to 260 nm, enhancing endocytosis and photodynamic therapy outcomes.
Sisi Yuan +6 more
wiley +2 more sources
Dihydrochalcones and Diterpenoids from Pteris ensiformis and Their Bioactivities
Molecules, 2017 Two new dihydrochalcone enantiomers (+)-1 and (−)-1, along with eight known compounds 3–10, were obtained from Pteris ensiformis. The planar structures were determined on the basis of extensive 1D and 2DNMR and HRESIMS.
Yu-Sheng Shi +5 more
doaj +1 more source
Stemarane Diterpenes and Diterpenoids
International Journal of Molecular Sciences, 2019 In this article the scientific activity carried out on stemarane diterpenes and diterpenoids, isolated over the world from various natural sources, was reviewed. The structure elucidation of stemarane diterpenes and diterpenoids was reported, in addition to their biogenesis and biosynthesis.
Leonelli, Francesca +3 more
openaire +2 more sources
Diterpenoid alkaloids from two species of Delphinium
, 2022 Four new compounds (1–4) were isolated from the whole plants of two species of Delphinium, including two C20-diterpenoid alkaloids, umbrodines A and B (1 and 2), and a dibenzoxazepinone, umbrolide A (3) from Delphinium umbrosum Hand.-Mazz.
Xian-Li Zhou (2676346) +7 more
core +1 more source
A new diterpenoid from Rhizophora apiculata
, 2011 A new diterpenoid from Rhizophora apiculataA new diterpenoid, 15(S)-isopimar-7-en-1-oxo-15,16-diol (1), was isolated from the stems of mangrove plant Rhizophora apiculata.
Xiao, Hong-Bin +10 more
core +1 more source
Molecular Docking and Dynamic Diterpenoid-Stevia Compounds from Water Maceration-Sonification Extract as Amylase and Glucosidase Enzyme Inhibits [PDF]
Brazilian Archives of Biology and TechnologyStevia (Stevia rebaudiana), with its intense sweetness, therapeutic properties, and safety profile, serves not only as a sugar substitute but also promotes holistic metabolic health.
Sentot Joko Raharjo +4 more
doaj +1 more source
Antifungal Activities of Compounds Produced by Newly Isolated Acrocarpospora Strains
Antibiotics, 2023 In our continued search for bioactive metabolites from cultures of rare Actinobacteria resources from all over Taiwan and various natural ecological environments, an active antimicrobial strain of Acrocarpospora punica 04107M was collected in Taitung ...
Ming-Jen Cheng +4 more
doaj +1 more source
Bioactive Natural Spirolactone-Type 6,7-seco-ent-Kaurane Diterpenoids and Synthetic Derivatives
Molecules, 2018 Diterpenoids are widely distributed natural products and have caused considerable interest because of their unique skeletons and antibacterial and antitumor activities and so on.
Haonan Li +9 more
doaj +1 more source
Further Studies on Structure-Cardiac Activity Relationships of Diterpenoid Alkaloids
Natural Product Communications, 2015 The cardiac effect of thirty-eight diterpenoid alkaloids was evaluated on the isolated bullfrog heart model. Among them, twelve compounds exhibited appreciable cardiac activity, with compounds 3 and 35 being more active than the reference drug lanatoside.
Zhong-Tang Zhang +7 more
doaj +1 more source
Archives of Medical Science, 2020 Introduction The present study evaluated the pro-survival signaling pathway inhibition potential of jatrophone in glioblastoma cells with the intention to develop effective treatment for glioblastoma.
Lei Yuan +6 more
doaj +1 more source