Bioactive Compounds From Torbangun [Plectranthus Amboinicus (Lour.) Spreng] Chloroform Fraction Induce Apoptosis in Breast Cancer (Mcf-7 Cells) in Vitro [PDF]
, 2017 Torbangun (Plectranthus amboinicus (Lour.) Spreng) is a medicinal plant that has been traditionally used in tropical countries to cure various illnesses.
Andarwulan, N. (Nuri) +3 more
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Bioactive Compounds from Euphorbia usambarica Pax. with HIV-1 Latency Reversal Activity
Pharmaceuticals, 2021 Euphorbia usambarica is a traditional medicine used for gynecologic, endocrine, and urogenital illnesses in East Africa; however, its constituents and bioactivities have not been investigated.
Yu-Chi Tsai +9 more
doaj +1 more source
Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway
British Journal of Pharmacology, EarlyView.Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu +4 more
wiley +1 more source
A new anti-feedant clerodane diterpenoid from tinospora cordifolia [PDF]
, 2013 Phytochemical investigation of the chloroform extract of Tinospora cordifolia yielded a new clerodane diterpenoid tincordin (1) along with tinosporide (2), 8-hydroxytinosporide (3), columbin (4), 8-hydroxycolumbin (5) and 10-hydroxycolumbin (6).
Campos, Ana M. F. Oliveira +3 more
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Rational Design for the Complete Synthesis of Stevioside in Saccharomyces cerevisiae
MicroorganismsStevioside is a secondary metabolite of diterpenoid glycoside production in plants. It has been used as a natural sweetener in various foods because of its high sweetness and low-calorie content.
Wei Huang +5 more
doaj +1 more source
Novel Antifungal Dimers from the Roots of Taiwania cryptomerioides
Molecules, 2022 Five new dimer compounds, namely Taiwaniacryptodimers A–E (1–5), were isolated from the methanol extract of the roots of Taiwania cryptomerioides. Their structures were established by mean of spectroscopic analysis and comparison of NMR data with those ...
Ming-Jen Cheng +5 more
doaj +1 more source
The FEBS Journal, EarlyView.We have converted the only known true bacterial monoterpene synthase, cineole synthase from Streptomyces clavuligerus (bCinS, C10 substrate), to a highly competent sesquiterpene synthase (C15) with a minimum number of rational mutations. By comparison with diterpene synthases (C20), we were then able to bestow diterpene synthase activity on bCinS. This
Nicole G. H. Leferink +3 more
wiley +1 more source
Paxilline negative mutants of Penicillium paxilli generated by heterologous and homologous plasmid integration : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Molecular Genetics at Massey University, Palmerston North, New Zealand [PDF]
, 1998 Using a monoclonal antibody-based ELISA, 600 pAN7-1 plasmid-tagged mutants of Penicillium paxilli were screened for paxilline accumulation and one paxilline negative mutant, YI-20, was identified (Itoh, unpublished data).
Young, Carolyn Anne
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Amber imitation? Two unusual cases of Pinus resin-coated beads in Iberian Late Prehistory (3rd and 2nd millennia BC) [PDF]
, 2019 A group of beads from the artificial cave of La Molina (Lora de Estepa, Sevilla) and Cova del Gegant (Sitges, Barcelona) were made from a biogenic raw material and intentionally covered by a layer of resin.
Avilés Escaño, Miguel Ángel +5 more
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Biological Profiling of Semisynthetic C19-Functionalized Ferruginol and Sugiol Analogues
Antibiotics, 2021 The abietane-type diterpenoids are significant bioactive compounds exhibiting a varied range of pharmacological properties. In this study, the first synthesis and biological investigation of the new abietane-diterpenoid (+)-4-epi-liquiditerpenoid acid ...
Miguel A. González-Cardenete +7 more
doaj +1 more source