Results 21 to 30 of about 271,886 (306)

Novel Method to Process Cystic Fibrosis Sputum for Determination of Oxidative State [PDF]

, 2010
Background: Induced sputum is the most commonly used method to analyze airway inflammation in cystic fibrosis (CF) patients ex vivo. Due to the complex matrix of the sample material, precise and reliable analysis of sputum constituents depends critically
Feilcke, M., Griese, M., Hartl, D., Hector, A., Jonas, F., Kappler, M.   +5 more
core   +1 more source

Daratumumab (Anti-CD38) interference with serological testing: An emerging challenge for blood banks in developing countries

Global Journal of Transfusion Medicine, 2017
Daratumumab (DARA), a monoclonal anti-CD38 antibody, belongs to the new generation of immunotherapy in refractory relapsed multiple myeloma. CD38 is weakly expressed on human erythrocytes.
Rasika Setia, Mitu Dogra, Prerna Sachdeva, Anil Handoo, Dharma Choudhary, Amit Agarwal   +5 more
doaj   +1 more source

Utility of dithiothreitol in a case of spontaneous autoagglutination due to mixed autoimmune hemolytic anemia in a child – A rare scenario

Global Journal of Transfusion Medicine, 2023
Mixed autoimmune hemolytic anemia (AIHA) represents
Rajeswari Subramaniyan
doaj   +1 more source

DNA intercalation and cleavage of an antitumor antibiotic dynemicin that contains anthracycline and enediyne cores [PDF]

, 1990
Dynemicin is a hybrid containing anthraquinone and enediyne cores, which contribute to binding and cleavage of DNA, respectively. DNA strand scission by the antitumor antibiotic is significantly enhanced by the addition of NADPH or thiol compounds.
Konishi, Masataka, Oki, Toshikazu, Shiraki, Takashi, Sugiura, Yukio   +3 more
core   +1 more source

Apolipoprotein[a] secretion from hepatoma cells is regulated in a size-dependent manner by alterations in disulfide bond formation

Journal of Lipid Research, 2003
Apolipoprotein[a] (apo[a]) is a large disulfide linked glycoprotein synthesized by hepatocytes. We have examined the role of disulfide bond formation in the processing of apo[a] using human and rat hepatoma cells expressing apo[a] isoforms containing ...
Fatiha Nassir, Yan Xie, Nicholas O. Davidson   +2 more
doaj   +1 more source

Experience With the Use of the MicroDTTect Device for the Diagnosis of Low-Grade Chronic Prosthetic Joint Infections in a Routine Setting

Frontiers in Medicine, 2021
Background: In prosthetic joint infections (PJIs), identification of the causative microorganisms is critical to successfully adapt and optimize treatment.
Camille Kolenda, Camille Kolenda, Camille Kolenda, Jérôme Josse, Jérôme Josse, Cécile Batailler, Cécile Batailler, Allison Faure, Alice Monteix, Sébastien Lustig, Sébastien Lustig, Tristan Ferry, Tristan Ferry, Tristan Ferry, Frédéric Laurent, Frédéric Laurent, Frédéric Laurent, Céline Dupieux, Céline Dupieux, Céline Dupieux   +19 more
doaj   +1 more source

Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA [PDF]

, 1987
Forms of the DNA double helix containing non-Watson-Crick base-pairing have been discovered recently based on x-ray diffraction analysis of quinoxaline antibiotic-oligonucleotide complexes.
Dervan, Peter B., Mendel, David
core   +2 more sources

Resolving crossmatch incompatibility due to daratumumab in multiple myeloma

Global Journal of Transfusion Medicine, 2020
Daratumumab (DARA) is an anti-CD38 monoclonal antibody which has promising results in relapsed and refractory multiple myeloma. DARA interferes with blood compatibility testing by causing panagglutination in the indirect antiglobulin test.
S Anuragaa, Dibyajyoti Sahoo, B Abhishekh   +2 more
doaj   +1 more source

Targeting the Ets Binding Site of the HER2/neu Promoter with Pyrrole-Imidazole Polyamides [PDF]

, 2000
Three DNA binding polyamides (1-3) were synthesized that bind with high affinity (Ka = 8.7·10^9 M^-1 to 1.4·10^10 M^-1) to two 7-base pair sequences overlapping the Ets DNA binding site (EBS; GAGGAA) within the regulatory region of the HER2/neu proximal ...
Beerman, Terry A., Benz, Chris C., Bürli, Roland W., Chiang, Shu-Yuan, Dervan, Peter B., Gawron, Loretta, Scott, Gary K.   +6 more
core   +1 more source

cAMP activates adenylate and guanylate cyclase of Dictyostelium discoideum cells by binding to different classes of cell-surface receptors. A study with extracellular Ca2+ [PDF]

, 1985
cAMP induces a transient increase of cAMP and cGMP levels in Dictyostelium discoideum cells. Fast binding experiments reveal three types of cAMP-binding site (S, H and L), which have different off-rates (t0.5, 0.7-15 s) and different affinities (Kd, 15 ...
Brachet, Bumann, De Wit, Devreotes, Dinauer, Gerisch, Gerisch, Janssens, Juliani, Kay, Konijn, Leichtling, Marin, Mato, Pannbacker, Roos, Schaap, Shaffer, Stadel, Toews, Van Haastert, Van Haastert, Van Haastert, Van Haastert, Van Haastert, Van Haastert   +25 more
core   +3 more sources