Results 121 to 130 of about 327,043 (288)

Heteroatom‐Mediated Covalent Organic Framework Membranes With Nitrogen‐Enriched Nanochannels for Efficient Desalination

open access: yesAdvanced Science, EarlyView.
Heteroatom precursor engineering serves as a molecular‐level strategy to tailor hydrazide monomer reactivity and diffusion kinetics, enabling controlled assembly of highly crystalline COF membranes with ultramicroporous channels. The nitrogen‐enriched nanochannels deliver high water/ion selectivity via simultaneous water transport acceleration and ion ...
Guishan Hu   +8 more
wiley   +1 more source

Thermo-Responsivity of the Polyacrylate-Adsorbed Metal Cation and its Hydration Structure

open access: yesAdsorption Science & Technology, 2008
The thermo-responsive phase behaviour of the sodium salt of poly(acrylic acid) (PAA) was studied when its counter-ion was exchanged for a series of metal cations (PAA–metal cation complexes).
Yoshimi Seida   +3 more
doaj   +1 more source

Restoration of m6A‐Modified circPSMB1 Suppresses Chordoma Progression and Enables Local Nanotherapeutic Intervention

open access: yesAdvanced Science, EarlyView.
An m6A‐modified circRNA, circPSMB1, is identified as a tumor suppressor in chordoma. METTL3‐dependent m6A promotes circPSMB1 interaction with HNRNPA2B1, limiting c‐MYC expression and malignant progression. An injectable HMnO2‐based nanohydrogel enables local circPSMB1 delivery and tumor microenvironment‐responsive therapy, offering a promising strategy
Yingchuang Tang   +7 more
wiley   +1 more source

The Sorption of Metals on the Polysulfone Cation Exchange Membranes

open access: yes, 2001
The sorption of NaCl and CaCl2 and monovalent-divalent cation salt mixtures on the polysulfone and polysulfone with polyester support cation exchange membranes were investigated.
Güğül, İlkay Hilal   +4 more
core  

Distinct Cleavage Trajectories Mediated by DNA and RNA Substrate in Argonaute From Methanocaldococcus Fervens

open access: yesAdvanced Science, EarlyView.
This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang   +9 more
wiley   +1 more source

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

open access: yesAdvanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka   +10 more
wiley   +1 more source

Networked salt-bridges mediate magnesium-dependent conformational dynamics and functional regulation in type IA topoisomerases

open access: yesNature Communications
Protein conformational dynamics are fundamental to enzyme function, yet the molecular mechanisms by which these dynamics are regulated remain poorly understood. Here, we reveal that a conserved network of salt-bridges, modulated by magnesium ions, serves
Yeonee Seol   +2 more
doaj   +1 more source

Monovalent and divalent cation effects on phase transitions of iota-carrageenan

open access: yes, 2007
Phase transitions Of L-carrageenan in a variety of monovalent (Li, Na, K) and divalent (Mg, Ca, Sr) cation solutions were studied during heating and cooling by using photon transmission technique.
Arda, Ertan   +3 more
core   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

open access: yesAdvanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie   +7 more
wiley   +1 more source

Defect‐Engineered LiYO2 Interlayers Enabling Fast Interfacial Li+ Transport in All‐Solid‐State Batteries

open access: yesAdvanced Science, EarlyView.
Defect‐engineered LiYO2 interlayers are designed through aliovalent Zn2+ and Zr4+ substitution to regulate Li+ point‐defect chemistry in Ni‐rich cathodes. Compared with Li‐excess‐type LYZnO, Li‐vacancy‐type LYZrO enables faster Li+ transport, suppresses Li6PS5Cl decomposition, lowers interfacial resistance, and mitigates polarization growth, thereby ...
Sodam Kim   +6 more
wiley   +1 more source

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