Results 221 to 230 of about 241,731 (297)

Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray

open access: yesChemFoodChem, EarlyView.
This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi   +2 more
wiley   +1 more source

Multivalent RNA‐Cleaving Agents on a Cubic Octameric Silsesquioxane Core

open access: yesChemistry – A European Journal, EarlyView.
RNA‐cleaving agents on a cubic octameric silsesquioxane core were synthesized and characterized. Several catalytic systems of these structures were screened using hexaribonucleotide models. The best systems were then further used to study their catalytic efficiency in cleaving a HER2 mRNA model sequence. The induced cleavage sites were also determined.
Hanni Haapsaari, Iris Tuomi, Pasi Virta
wiley   +1 more source

Structure and Dynamics of Porin Loops in Asymmetric Outer Membranes of E. coli

open access: yesChemistry – A European Journal, EarlyView.
What are loops of membrane proteins doing within the oligosaccharide coat of cells? This structurally unexplored space is studied by solid‐state NMR, with the outer membrane protein G (OmpG) embedded in asymmetric E. coli outer membrane (OM) vesicles as a paradigmatic example.
Morgane Adélaïde   +13 more
wiley   +1 more source

Modulation of Epigenetic Control by Advanced Molecular Tweezers

open access: yesChemistry – A European Journal, EarlyView.
Tailored dimeric molecular tweezers recognize the DNA‐binding part of Histone H4 and interrupt the essential histone‐DNA interaction. ABSTRACT This work addresses the question if supramolecular systems can be tailored to interfere with posttranslational modifications (PTM) and epigenetics.
My‐Hue‐Le   +9 more
wiley   +1 more source

Towards Halogen Bonding MOFs: Networking With a Polyiodinated and Perfluorinated Terphenyl Ligand and Divalent Zinc

open access: yesChemistry – A European Journal, EarlyView.
One ligand, three new architectures with different intermolecular interactions: a polyhalogenated terphenyl linker with carboxyl groups coordinates Zn2+ to form (i) a metal‐containing hydrogen‐bonded organic framework; (ii) a metal‐organic framework or (iii) one‐dimensional metal‐organic chains with intermolecular halogen bonding and hydrogen bonding ...
Elad Gaver   +8 more
wiley   +1 more source

Persilylated and Related Silyl Anion‐Induced Synthesis of Group 3–10 Metal–Silyl Complexes

open access: yesChemistry – A European Journal, EarlyView.
Persilylated and related silyl anions serve as powerful tools for constructing metal–silyl complexes across group 3–10 elements. Their strong σ‐donating ability and steric bulk stabilize low‐coordinate, reactive species and enable unique bonding motifs.
Yusuke Sunada
wiley   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

open access: yesChemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi   +6 more
wiley   +1 more source

Uncatalyzed Guanosine Phosphorylation under Potentially Prebiotic Conditions

open access: yesChemistry – A European Journal, EarlyView.
Pyrophosphate acts as phosphorylating agent of guanosine under simple wet‐dry cycles without condensing agent and inorganic catalysts to afford cyclic guanosine monophosphate derivatives useful for oligomerization in prebiotic processes. ABSTRACT The phosphorylation of nucleosides and their subsequent polymerization are key issues in the study of the ...
Martina Proietti   +5 more
wiley   +1 more source

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